Dabrafenib Impurity 29 CAS CATO-C4X-303329
| CAS No. | CATO-C4X-303329 |
| Molecular Formula | C15H12F2N2O3 |
| Molecular Weight | 306.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Dabrafenib Impurity 29 (CAS CATO-C4X-303329, C15H12F2N2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C15H12F2N2O3, Dabrafenib Impurity 29 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 306.26 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Dabrafenib Impurity 29 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H12F2N2O3 |
| Molecular Weight | 306.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Dabrafenib Standards
- Dabrafenib Impurity 35 (CAS CATO-C4X-303335)
- Dabrafenib Impurity 25 (CAS 1353575-68-4)
- Dabrafenib Impurity 39 (CAS CATO-C4X-303339)
- Dabrafenib Impurity 20 (CAS CATO-C4X-303320)
- Dabrafenib Impurity 28 (CAS CATO-C4X-303328)
- Dabrafenib Impurity 27 (CAS CATO-C4X-303327)
- Dabrafenib Impurity 3 (CAS CATO-C4X-30333)
- Dabrafenib Impurity 33 (CAS CATO-C4X-303333)
Recommended Standards
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- Quinoxidine (Chinoxidin) (CAS 10103-89-6)
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- 2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5R-oxazolidine carboxylic acid (CAS 1160170-07-9)
- Malic Acid Impurity 3 (CAS 66178-02-7)
- Brivaracetam Impurity 132 (CAS CATO-C4X-2007132)
- Tenofovir alafenamide Impurity 94 (CAS CATO-C4X-179794)
- Cabozantinib Impurity 44 (CAS CATO-C4X-201844)
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- 1H-Pyrazolo[4,3-d]pyrimidin-5-amine (CAS 1314935-81-3)
- (2R,5R)-5-(4-chlorobenzyl)-2-methylmorpholine (CAS 2306253-07-4)
- 6-Chloro-4-(methylsulfanyl)-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6,10,12-hexaene (CAS 478077-24-6)
- 5-Isopropyl-1-propyl-1h-1,2,3-triazole-4-carboxylic acid (CAS 1247760-00-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com