Lemborexant Impurity 68 CAS CATO-C4X-304268
| CAS No. | CATO-C4X-304268 |
| Molecular Formula | C10H6F2N4 |
| Molecular Weight | 220.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Lemborexant Impurity 68 (CAS CATO-C4X-304268), a pharmacopoeial impurity reference standard (molecular formula C10H6F2N4, MW 220.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Lemborexant Impurity 68 (C10H6F2N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H6F2N4 |
| Molecular Weight | 220.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Lemborexant Standards
- Lemborexant impurity 18 (CAS CATO-C4X-304218)
- Lemborexant Impurity 80 (CAS 2227744-56-9)
- Lemborexant Impurity 99 (CAS CATO-C4X-304299)
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- Lemborexant Impurity 65 (CAS 3070371-35-3)
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- Lemborexant Impurity 95 (CAS 3070371-42-2)
- Lemborexant Impurity 96 (CAS CATO-C4X-304296)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com