Abemaciclib Impurity 13 CAS 1648707-16-7
| CAS No. | 1648707-16-7 |
| Molecular Formula | C21H20F2N6O |
| Molecular Weight | 410.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Abemaciclib Impurity 13.
CATO supplies Abemaciclib Impurity 13 (CAS 1648707-16-7), a pharmacopoeial impurity reference standard (molecular formula C21H20F2N6O, MW 410.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Abemaciclib Impurity 13 (C21H20F2N6O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Abemaciclib Impurity 13 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H20F2N6O |
| Molecular Weight | 410.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Abemaciclib Standards
- Abemaciclib Impurity 145 (CAS CATO-C4X-2937145)
- Abemaciclib Impurity 54 (CAS CATO-C4X-293754)
- Abemaciclib Impurity 12 (CAS 1627082-92-1)
- Abemaciclib Impurity 92 (CAS CATO-C4X-293792)
- Abemaciclib Impurity 57 (CAS CATO-C4X-293757)
- Abemaciclib Impurity 161 (CAS CATO-C4X-2937161)
- Abemaciclib Impurity 10 (CAS CATO-C4X-293710)
- Abemaciclib Impurity 34 (CAS CATO-C4X-293734)
Recommended Standards
- Serotonin Impurity 3 (CAS CATO-C4X-25343)
- Lemborexant impurity 19 (CAS 2541020-19-1)
- Ceftibuten Impurity 8 (CAS 97519-40-9)
- Lemborexant impurity 6 (CAS 3070371-41-1)
- (E)-Ceftizoxime Impurity 20 (CAS CATO-C4X-179320)
- Levodropropizine EP Impurity A (Dextrodropropizine) (CAS 99291-24-4)
- Pranoprofen Impurity 40 (CAS CATO-C4X-181140)
- 2-Acetyl-N-benzylhydrazine-1-carbothioamide (CAS 94267-75-1)
- 4-(Benzo[d]thiazol-2-ylthio)-3-nitrobenzyl 3-methylbenzoate (CAS 320424-21-3)
- 3-(3-fluoro-4-methoxyphenyl)pyrrolidine (CAS 1260815-20-0)
- 3-(tert-Butyl)-5-cyclopropoxy-N-methylpyridin-2-amine (CAS 1243381-62-5)
- 2-Amino-5-methoxybenzonitrile (CAS 23842-82-2)
- 2-(2-Fluorophenoxy)-5-methylaniline (CAS 946682-88-8)
- MCH-Gene-Overprinted-Polypeptide-14 (rat) (H-4746.0500) (CAS 182917-44-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com