Lefamulinum Impurity 37 CAS CATO-C4X-304737
| CAS No. | CATO-C4X-304737 |
| Molecular Formula | C15H16F3NO3S |
| Molecular Weight | 347.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lefamulinum Impurity 37.
As a process- or degradation-related impurity, Lefamulinum Impurity 37 (CAS CATO-C4X-304737, C15H16F3NO3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Lefamulinum Impurity 37 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 347.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H16F3NO3S |
| Molecular Weight | 347.35 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Lefamulinum Standards
- Lefamulinum Impurity 34 (CAS CATO-C4X-304734)
- Lefamulinum Impurity 39 (CAS CATO-C4X-304739)
- Lefamulinum Impurity 40 (CAS CATO-C4X-304740)
- Lefamulinum Impurity 12 (CAS CATO-C4X-304712)
- Lefamulinum Impurity 13 (CAS CATO-C4X-304713)
- Lefamulinum Impurity 47 (CAS CATO-C4X-304747)
- Lefamulinum Impurity 48 (CAS CATO-C4X-304748)
- Lefamulinum Impurity 10 (CAS CATO-C4X-304710)
Recommended Standards
- Tiamulin impurity 10 (CAS CATO-C4X-221010)
- Valnemulin impurity 7 (CAS 1350636-92-8)
- N-({2-[2-(4-Fluorophenoxy)acetyl]hydrazino}carbothioyl)benzenecarboxamide (CAS 1022873-90-0)
- Piroxicam Impurity 18 (CAS CATO-C4X-173318)
- Gliquidone Impurity 10 (CAS CATO-C4X-300010)
- Azelnidipine Impurity 4 (CAS 1655504-77-0)
- Eldecalcitol Impurity 51 (CAS 1527523-12-1)
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- N-(sec-butyl)-5-(1-tosylpiperidin-2-yl)pyridin-2-amine (CAS 1352514-84-1)
- N-Me-cis-Hyp-OH (CAS 67463-44-9)
- 2-(3-Amino-5,6-dihydrocyclopenta[c]pyrazol-2(4h)-yl)acetic acid (CAS 1493259-67-8)
- 6-(4-BRomophenyl)-2-(4-fluorophenyl)imidazo[2,1-b][1,3]thiazole (CAS 881040-03-5)
- Methyl 4-acetoxy-6-(decyloxy)-7-isopropoxyquinoline-3-carboxylate (CAS 80061-37-6)
- TRAF6 Control Peptide trifluoroacetate salt (CAS 852690-80-3)
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