Lefamulinum Impurity 48 CAS CATO-C4X-304748
| CAS No. | CATO-C4X-304748 |
| Molecular Formula | C22H34O4 |
| Molecular Weight | 362.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Lefamulinum Impurity 48 (CAS CATO-C4X-304748, C22H34O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Lefamulinum Impurity 48 (C22H34O4) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 362.50 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lefamulinum Impurity 48 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H34O4 |
| Molecular Weight | 362.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Lefamulinum Standards
- Lefamulinum Impurity 47 (CAS CATO-C4X-304747)
- Lefamulinum Impurity 12 (CAS CATO-C4X-304712)
- Lefamulinum Impurity 13 (CAS CATO-C4X-304713)
- Lefamulinum Impurity 35 (CAS CATO-C4X-304735)
- Lefamulinum Impurity 46 (CAS CATO-C4X-304746)
- Lefamulinum Impurity 34 (CAS CATO-C4X-304734)
- Lefamulinum Impurity 37 (CAS CATO-C4X-304737)
- Lefamulinum Impurity 39 (CAS CATO-C4X-304739)
Recommended Standards
- Phthalic acid, bis-5-methylhexyl ester (CAS 90937-19-2)
- Tiamulin EP Impurity J (CAS 31771-36-5)
- Diheptyl phthalate (CAS 3648-21-3)
- Tiamulin EP Impurity K (CAS 31716-11-7)
- Terazidone Impurity 1 (CAS CATO-C4X-30541)
- Moxifloxacin Impurity 36 (CAS 1395056-42-4(free base）)
- Olmesartan Impurity 86 (CAS 883681-10-4)
- Potassium 2.2.3,3-tetrafluoropropionate (CAS 71592-16-0)
- (3S,5R)-3-Hydroxy-5-methyldihydrofuran-2(3H)-one (CAS 34644-78-5)
- Ethyl 2-bromo-6-cyano-3-(difluoromethyl)benzoate (CAS 1806060-45-6)
- 4,4'-Disulfanediylbis(2-fluoroaniline) (CAS 16766-33-9)
- Sodium Pyrene-1,3,6,8-tetrasulfonate (CAS 59572-10-0)
- N-(5-Methylisoxazol-4-yl)formamide (CAS 100499-62-5)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com