Lefamulinum Impurity 40 CAS CATO-C4X-304740
| CAS No. | CATO-C4X-304740 |
| Molecular Formula | C15H16F3NO3S |
| Molecular Weight | 347.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Lefamulinum Impurity 40 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Lefamulinum Impurity 40 (CAS CATO-C4X-304740, C15H16F3NO3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lefamulinum Impurity 40 (C15H16F3NO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C15H16F3NO3S |
| Molecular Weight | 347.35 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Lefamulinum Standards
- Lefamulinum Impurity 34 (CAS CATO-C4X-304734)
- Lefamulinum Impurity 37 (CAS CATO-C4X-304737)
- Lefamulinum Impurity 39 (CAS CATO-C4X-304739)
- Lefamulinum Impurity 12 (CAS CATO-C4X-304712)
- Lefamulinum Impurity 13 (CAS CATO-C4X-304713)
- Lefamulinum Impurity 47 (CAS CATO-C4X-304747)
- Lefamulinum Impurity 48 (CAS CATO-C4X-304748)
- Lefamulinum Impurity 10 (CAS CATO-C4X-304710)
Recommended Standards
- N-({2-[2-(4-Fluorophenoxy)acetyl]hydrazino}carbothioyl)benzenecarboxamide (CAS 1022873-90-0)
- n-((2s,3r,4r,5s,6r)-4,5-Dihydroxy-6-(hydroxymethyl)-2-(naphthalen-1-yloxy)tetrahydro-2h-pyran-3-yl)acetamide (CAS 10329-98-3)
- 1-Naphthyl 2-acetamido-2-deoxy-b-D-galactopyranoside (CAS 1191421-21-2)
- Tiamulin impurity 10 (CAS CATO-C4X-221010)
- Butylphthalide Impurity N5 (CAS 169141-21-3)
- Paclitaxel Impurity 63 (CAS 959032-68-9)
- Carbazochrome Impurity 39 (CAS CATO-C4X-229139)
- tert-Butyl 2-(methylthio)-5,6,7,9-tetrahydro-8H-pyrimido[5,4-e][1,4]diazepine-8-carboxylate (CAS 1251000-26-6)
- Butyl 3-bromo-2-chloroisonicotinate (CAS 2379322-37-7)
- Sunitinib Impurity 81 (CAS CATO-C4X-133381)
- 1-[5-[1-(tert-Butoxy)ethyl]-1-(3-fluoro-4-methylbenzyl)-2-piperazinyl]-1-ethanol (CAS 1353505-79-9)
- Baclofen impurity 28 (CAS CATO-C4X-101228)
- 1,7,7-TRimethylbicyclo[2.2.1]hept-2-yl isocyanide (CAS 1301732-92-2)
- Delta-Sleep Inducing Peptide (CAS 62568-57-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com