Lefamulinum Impurity 5 CAS CATO-C4X-30475
| CAS No. | CATO-C4X-30475 |
| Molecular Formula | C22H34O6 |
| Molecular Weight | 394.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lefamulinum Impurity 5.
CATO supplies Lefamulinum Impurity 5 (CAS CATO-C4X-30475), a pharmacopoeial impurity reference standard (molecular formula C22H34O6, MW 394.50 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Lefamulinum Impurity 5 (C22H34O6) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H34O6 |
| Molecular Weight | 394.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Lefamulinum Standards
- Lefamulinum Impurity 49 (CAS CATO-C4X-304749)
- Lefamulinum Impurity 45 (CAS CATO-C4X-304745)
- Lefamulinum Impurity 21 (CAS CATO-C4X-304721)
- Lefamulinum Impurity 35 (CAS CATO-C4X-304735)
- Lefamulinum Impurity 46 (CAS CATO-C4X-304746)
- Lefamulinum Impurity 47 (CAS CATO-C4X-304747)
- Lefamulinum Impurity 48 (CAS CATO-C4X-304748)
- Lefamulinum Impurity 12 (CAS CATO-C4X-304712)
Recommended Standards
- Tiamulin impurity 18 (CAS CATO-C4X-221018)
- Bixin (CAS 6983-79-5)
- Tiamulin impurity 11 (CAS CATO-C4X-221011)
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- Fudosteine Impurity 24 (CAS CATO-C4X-144724)
- Suzetrigine Impurity 52 (CAS CATO-C4X-336952)
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- Evocalcet Impurity 43 (CAS 870859-14-6)
- 3-Hydroxy-4-(1-naphthyloxy)-butanenitrile (CAS 20804-76-6)
- D-Glu3-Tirzepatide (CAS CATO-CPTD788927)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com