Lefamulinum Impurity 46 CAS CATO-C4X-304746
| CAS No. | CATO-C4X-304746 |
| Molecular Formula | C22H32O5 |
| Molecular Weight | 376.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Lefamulinum Impurity 46 (CAS CATO-C4X-304746, C22H32O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lefamulinum Impurity 46 (C22H32O5) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C22H32O5 |
| Molecular Weight | 376.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Lefamulinum Standards
- Lefamulinum Impurity 35 (CAS CATO-C4X-304735)
- Lefamulinum Impurity 21 (CAS CATO-C4X-304721)
- Lefamulinum Impurity 45 (CAS CATO-C4X-304745)
- Lefamulinum Impurity 47 (CAS CATO-C4X-304747)
- Lefamulinum Impurity 48 (CAS CATO-C4X-304748)
- Lefamulinum Impurity 5 (CAS CATO-C4X-30475)
- Lefamulinum Impurity 12 (CAS CATO-C4X-304712)
- Lefamulinum Impurity 13 (CAS CATO-C4X-304713)
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