Selumetinib Impurity 22 CAS CATO-C4X-305322
| CAS No. | CATO-C4X-305322 |
| Molecular Formula | C10H10FN3O2 |
| Molecular Weight | 223.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Selumetinib Impurity 22 (C10H10FN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 223.20 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Selumetinib Impurity 22 (CAS CATO-C4X-305322), a pharmacopoeial impurity reference standard (molecular formula C10H10FN3O2, MW 223.20 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Selumetinib Impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10FN3O2 |
| Molecular Weight | 223.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Selumetinib Standards
- Selumetinib Impurity N1 (CAS 917980-11-1)
- Selumetinib Impurity 15 (CAS CATO-C4X-305315)
- Selumetinib Impurity 13 (CAS CATO-C4X-305313)
- Selumetinib Impurity 14 (CAS CATO-C4X-305314)
- Selumetinib Impurity 5 (CAS CATO-C4X-30535)
- Selumetinib Impurity 18 (CAS CATO-C4X-305318)
- Selumetinib Impurity 9 (CAS CATO-C4X-30539)
- Selumetinib Impurity 16 (CAS CATO-C4X-305316)
Recommended Standards
- Cabozantinib Impurity 33 (CAS 849217-48-7)
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- 4-Pentafluoroethylsulfanyl-butylamine (CAS 1208078-79-8)
- Proparacaine Impurity 7 (CAS 35288-44-9)
- Regorafenib Impurity 19 (CAS 2098799-12-1)
- Cefodizime Impurity 22 (CAS CATO-C4X-180622)
- 6-((Trifluoromethyl)thio)-2,3-dihydrobenzofuran-3-amine (CAS 1273655-14-3)
- (R)-1-((6-Aminoquinolin-2-yl)methyl)pyrrolidin-3-ol (CAS 832102-05-3)
- 3-Amino-1-(3,4-dimethylphenyl)propan-1-ol (CAS 1082554-72-0)
- 5-(1-phenyl-1H-pyrazol-4-yl)-1,2-oxazole-4-carboxylic acid (CAS 1500627-24-6)
- Ethyl (2,6-dichloro-4-formylphenoxy)acetate (CAS 27445-09-6)
- 1,2-Di(pyridin-3-yl)ethane-1,2-diol (CAS 41668-21-7)
- Semaglutide impurity 91 (CAS CATO-C4X-222691)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com