Nitrofurantoin impurity 1 CAS CATO-C4X-30861
| CAS No. | CATO-C4X-30861 |
| Molecular Formula | C8H5N5O6 |
| Molecular Weight | 267.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C8H5N5O6, Nitrofurantoin impurity 1 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 267.16 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Nitrofurantoin impurity 1 (CAS CATO-C4X-30861, C8H5N5O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Nitrofurantoin impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5N5O6 |
| Molecular Weight | 267.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Nitrofurantoin Standards
- Nitrofurantoin-13C3 (CAS 1217226-46-4)
- Nitrofurantoin (CAS 67-20-9)
- Nitrofurantoin Impurity 3 (CAS CATO-C4X-30863)
- Nitrofurantoin Impurity N1 (CAS 91447-38-0)
- Nitrofurantoin Impurity 2 (CAS 777-34-4)
- Nitrofurantoin RC 1 (CAS 25004-91-5)
- Nitrofurantoin Monohydrate (CAS 17140-81-7)
- Nitrofurantoin Impurity 3 (CAS 1749-92-4)
Recommended Standards
- Gemcitabine EP Impurity C-13C-15N2 (CAS 1233921-75-9)
- 1-(4-Chlorophenyl)butane-1-sulfonyl chloride (CAS 1248955-64-7)
- tert-Butyl (4-bromobutyloxy)acetate (CAS 475086-55-6)
- 4-(2,5-Dichlorothiophen-3-yl)-2,2-dimethylbutanoic acid (CAS 1496679-65-2)
- Semaglutide impurity 01 (CAS 1998701-31-7)
- Trazodone Impurity 35 (CAS 142944-48-7（free base）)
- Mirabegron Impurity 76 (CAS CATO-C4X-103276)
- 1,1,3,3-Tetraethoxy-2,2-dimethylpropane (CAS 10602-38-7)
- 5,6-Difluoro-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione (CAS 172411-18-6)
- 5-(4-Methylthiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid (CAS 1526585-35-2)
- p-Iodoclonidine HCl (CAS 108294-57-1)
- Dipentamethylenethiuram hexasulfide(DPTT) (CAS 971-15-3)
- 3-(5-Methyl-1h-1,2,4-triazol-3-yl)benzoic acid hydrochloride (CAS 1375474-46-6)
- Tau Peptide (294-305) (human) trifluoroacetate salt (CAS 1428135-29-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com