Nitrofurantoin Impurity 3 CAS CATO-C4X-30863
| CAS No. | CATO-C4X-30863 |
| Molecular Formula | C10H8N4O7 |
| Molecular Weight | 296.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C10H8N4O7, Nitrofurantoin Impurity 3 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 296.19 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Nitrofurantoin Impurity 3 (CAS CATO-C4X-30863, C10H8N4O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8N4O7 |
| Molecular Weight | 296.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Nitrofurantoin Standards
- Nitrofurantoin impurity 1 (CAS CATO-C4X-30861)
- Nitrofurantoin-13C3 (CAS 1217226-46-4)
- Nitrofurantoin (CAS 67-20-9)
- Nitrofurantoin Impurity N1 (CAS 91447-38-0)
- Nitrofurantoin Impurity 2 (CAS 777-34-4)
- Nitrofurantoin RC 1 (CAS 25004-91-5)
- Nitrofurantoin Monohydrate (CAS 17140-81-7)
- Nitrofurantoin Impurity 3 (CAS 1749-92-4)
Recommended Standards
- 6-(bromomethyl)-3-phenyl-5H,6H-[1,2,4]triazolo[3,4-b][1,3]thiazole (CAS 742004-46-2)
- 2-bromo-N-(2,3-dihydro-1H-inden-5-yl)-3-methylbutanamide (CAS 1016519-25-7)
- 5-(4-Bromophenyl)-4-cyclopropyl-4H-1,2,4-triazole-3-thiol (CAS 919970-09-5)
- 2-Bromo-3-methyl-1-(2-methyl-2,3-dihydro-1h-indol-1-yl)butan-1-one (CAS 1017021-93-0)
- Cloransulam-Methyl Impurity 1 (CAS CATO-C4X-31701)
- Mirogabalin Impurity 15 (CAS CATO-C4X-292415)
- Tryptophan impurity 43 (CAS 77872-41-4)
- 2,5-Bis((trimethylsilyl)ethynyl)thiophene (CAS 79109-69-6)
- 2,4-Dichloro-N-methoxy-N-methylbenzamide (CAS 646528-36-1)
- 4-Iodomethyl-1-methyl-piperidine (CAS 1353989-49-7)
- Afatinib Impurity 50 (CAS 137131-09-0)
- 3-(3,4-Dimethoxyphenyl)-1-methyl-1H-pyrazole-5-carboxylic acid (CAS 93618-36-1)
- Ethyl 3-((2,2-dimethyl-1,3-dioxolan-4-yl)methoxy)-4,4,4-trifluorobutanoate (CAS 886505-47-1)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
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