Ribociclib Impurity 11 CAS CATO-C4X-310011
| CAS No. | CATO-C4X-310011 |
| Molecular Formula | C37H46N12O2 |
| Molecular Weight | 690.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ribociclib Impurity 11 (CAS CATO-C4X-310011), a pharmacopoeial impurity reference standard (molecular formula C37H46N12O2, MW 690.84 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ribociclib Impurity 11 (C37H46N12O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ribociclib Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C37H46N12O2 |
| Molecular Weight | 690.84 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 12 |
Related Ribociclib Standards
- Ribociclib Impurity 34 (CAS CATO-C4X-310034)
- Ribociclib Impurity 16 (CAS CATO-C4X-310016)
- Ribociclib Impurity 20 (CAS CATO-C4X-310020)
- Ribociclib Impurity 44 (CAS CATO-C4X-310044)
- Ribociclib Impurity 41 (CAS CATO-C4X-310041)
- Ribociclib Impurity 42 (CAS CATO-C4X-310042)
- Ribociclib impurity 1 (CAS CATO-C4X-31001)
- Ribociclib Impurity 21 (CAS CATO-C4X-310021)
Recommended Standards
- [2,7-Di(tert-butyl)-9,9-dimethylxanthene-4,5-diyl]bis(diphenylphosphine) (CAS 221462-97-1)
- Acetyl-PHF5 amide (CAS 1190970-24-1)
- (S)-3,3'-Bis[4-(2-naphthalenyl)phenyl]-[,1'-binaphthalene]-2,2'-diol (CAS 309934-87-0)
- Dalfopristin (CAS 112362-50-2)
- Perindopril Impurity 85 (CAS CATO-C4X-125285)
- Aminolevulinic Acid Related Compound B (CAS 109258-71-1)
- Sitagliptin Impurity 130 (CAS CATO-C4X-1144130)
- Lodoxamide Impurity N44 (CAS 14994-02-6)
- 4-Methyl-3(2H)-pyridazinone (CAS 33471-40-8)
- Heptene-2 (cis, trans) (CAS 592-77-8)
- 9-(3-Aminobenzyl)-2-chloro-N,N-dimethyl-9H-purin-6-amine (CAS 115204-71-2)
- 74672-11-0 1-Chloro-4-(4-methyl-4-pentenyl)benzene DTXSID50343030 (CAS 74672-11-0)
- 4-Methyl-N-(2-(piperazin-1-yl)ethyl)pentanamide hydrochloride (CAS 1827987-85-8)
- Liraglutide Impurity 20 TFA Salt (CAS CATO-C4X-199220)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com