Darolutamide Impurity 43 CAS CATO-C4X-310643
| CAS No. | CATO-C4X-310643 |
| Molecular Formula | C19H17ClN6O |
| Molecular Weight | 380.83 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Darolutamide Impurity 43 (CAS CATO-C4X-310643, C19H17ClN6O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Darolutamide Impurity 43 (C19H17ClN6O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H17ClN6O |
| Molecular Weight | 380.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Darolutamide Standards
- Darolutamide Impurity 44 (CAS CATO-C4X-310644)
- Darolutamide Impurity 25 (CAS CATO-C4X-310625)
- Darolutamide Impurity 38 (CAS CATO-C4X-310638)
- Darolutamide Impurity 27 (CAS 1297538-27-2)
- Darolutamide Impurity 30 (CAS CATO-C4X-310630)
- Darolutamide Impurity 26 (CAS CATO-C4X-310626)
- Darolutamide (CAS 1297538-32-9)
- Darolutamide impurity 10 (CAS 1976022-48-6)
Recommended Standards
- Fluvoxamine impurity 46 (CAS CATO-C4X-195146)
- N-(3-Chloro-4-fluorophenyl)-2-(2-(3-propyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)acetamide (CAS 1251612-15-3)
- N-(6-amino-1-benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-chloro-N-(3-methoxypropyl)acetamide (CAS 730950-29-5)
- 3-(2-Chloro-6-fluorobenzyl)-4-hydroxy-1-(3-morpholinopropyl)pyridin-2(1H)-one (CAS 477860-52-9)
- Phloroglucinol impurity 60 (CAS CATO-C4X-221760)
- Clenbuterol EP impurity C (CAS 37148-48-4)
- Cefdinir Impurity 98 (CAS CATO-C4X-121098)
- 1-(4-Ethoxy-3-(pyrrolidin-1-ylmethyl)phenyl)ethan-1-one (CAS 1179630-50-2)
- 1-Bromo-2-(1-fluoro-ethyl)-benzene (CAS 1027513-77-4)
- 6-Methoxyquinolin-3-amine hydrochloride (CAS 1170974-22-7)
- (E)-{[2-(4-chlorophenyl)-8-methylimidazo[1,2-a]pyridin-3-yl]methylidene}amino 3-(trifluoromethyl)benzoate (CAS 478248-55-4)
- 1-(Furan-2-carbonyl)-2-methylpiperazine (CAS 146951-80-6)
- 1,2,3,6-Tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine HCl (CAS 1121057-75-7)
- Des-Val23-Tirzepatide (CAS CATO-CPTD788950)
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