Phloroglucinol impurity 60 CAS CATO-C4X-221760
| CAS No. | CATO-C4X-221760 |
| Molecular Formula | C18H10O11 |
| Molecular Weight | 402.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Phloroglucinol impurity 60 is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Phloroglucinol impurity 60 (CAS CATO-C4X-221760) is a certified pharmaceutical impurity reference standard with the molecular formula C18H10O11 and a molecular weight of 402.27 g/mol.
The molecular framework of Phloroglucinol impurity 60 (C18H10O11) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H10O11 |
| Molecular Weight | 402.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Phloroglucinol Standards
- Phloroglucinol Tribenzyl Ether (CAS 59434-20-7)
- Phloroglucinol Impurity 50 (CAS 119290-91-4)
- Phloroglucinol Impurity X (CAS 31769-60-5)
- Phloroglucinol Impurity 37 (CAS CATO-C4X-221737)
- Phloroglucinol Impurity 40 (CAS CATO-C4X-221740)
- Phloroglucinol Impurity 41 (CAS 62218-04-6)
- Phloroglucinol impurity 51 (CAS CATO-C4X-221751)
- Phloroglucinol impurity 52 (CAS CATO-C4X-221752)
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- 2-(4-Methylpiperidin-2-yl)acetic acid (CAS 887587-46-4)
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