Carebastine Impurity 1 CAS CATO-C4X-31691

Description

Compared with other compounds in its class, the molecular weight of 268.74 g/mol gives Carebastine Impurity 1 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Carebastine Impurity 1 (CAS CATO-C4X-31691) is a certified pharmaceutical impurity reference standard with the molecular formula C14H17ClO3 and a molecular weight of 268.74 g/mol.

Carebastine Impurity 1 (C14H17ClO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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