Carebastine Impurity 5 CAS CATO-C4X-31695
| CAS No. | CATO-C4X-31695 |
| Molecular Formula | C16H21ClO3 |
| Molecular Weight | 296.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Carebastine Impurity 5 (C16H21ClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Carebastine Impurity 5 (CAS CATO-C4X-31695, C16H21ClO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Carebastine Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H21ClO3 |
| Molecular Weight | 296.79 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Carebastine Standards
- Carebastine Impurity 1 (CAS CATO-C4X-31691)
- Carebastine Impurity 6 (CAS CATO-C4X-31696)
- Carebastine Impurity 2 (CAS 2626068-21-9)
- Carebastine (CAS 90729-42-3)
- Carebastine Impurity 7 (CAS CATO-C4X-31697)
- Carebastine-D5 (CAS 1189661-02-6)
- Carebastine Methyl Ester (CAS 189064-48-0)
- Carebastine Impurity 3 (CAS CATO-C4X-31693)
Recommended Standards
- Pentoxyverine Impurity 14 (CAS CATO-C4X-227014)
- 2-Chloro-1-(4-(2-isopropyl-6-methylpyrimidin-4-yl)piperazin-1-yl)ethan-1-one (CAS 1306606-72-3)
- Dapoxetine Impurity 52 (CAS 1445281-25-3)
- 2-(1-Chloroethyl)-5-(thiophen-2-yl)-3h,4h-thieno[2,3-d]pyrimidin-4-one (CAS 733031-24-8)
- Diphenhydramine impurity 9 (CAS CATO-C4X-14249)
- Atrasentan Impurity 198 (CAS 173937-92-3)
- Isavuconazole Impurity 108 (CAS CATO-C4X-1236108)
- 6-(Aminomethyl)-N-methylpyridine-2-carboxamide (CAS 944150-29-2)
- 6-Aminoindole-3-carboxylic Acid (CAS 90417-29-1)
- 2-(3-Fluorophenyl)isonicotinic acid (CAS 1214350-69-2)
- 5-Bromo-2-chloro-n-ethyl-nicotinamide (CAS 1249312-18-2)
- 3-Amino-5-chloro-2-cyanothiophene (CAS 1017789-12-6)
- Methyl 2-(5-formylfuran-2-yl)benzoate (CAS 240121-97-5)
- Neuropeptide Y (3-36) (porcine) trifluoroacetate salt (CAS 143863-88-1)
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