Vazegepant Impurity 9 CAS CATO-C4X-32009
| CAS No. | CATO-C4X-32009 |
| Molecular Formula | C48H57N11O6 |
| Molecular Weight | 884.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Vazegepant Impurity 9 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Vazegepant Impurity 9 (CAS CATO-C4X-32009) is a certified pharmaceutical impurity reference standard with the molecular formula C48H57N11O6 and a molecular weight of 884.04 g/mol.
The molecular framework of Vazegepant Impurity 9 (C48H57N11O6) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C48H57N11O6 |
| Molecular Weight | 884.04 g/mol |
| Purity | ＞95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 26.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 11 |
Related Vazegepant Standards
- Vazegepant Impurity 8 (CAS CATO-C4X-32008)
- Vazegepant impurity 38 (CAS CATO-C4X-320038)
- Vazegepant impurity 39 (CAS CATO-C4X-320039)
- Vazegepant impurity 35 (CAS CATO-C4X-320035)
- Vazegepant Impurity 28 (CAS CATO-C4X-320028)
- Vazegepant Impurity 41 (CAS CATO-C4X-320041)
- Vazegepant Impurity 11 (CAS CATO-C4X-320011)
- Vazegepant Impurity 12 (CAS CATO-C4X-320012)
Recommended Standards
- 4-((6-Aminopyrimidin-4-yl)amino)benzenesulfonamide hydrochloride (CAS 21886-12-4)
- 1,1,1-Trifluoro-N-[(11bS)-4-oxido-2,6-bis[2,4,6-trisisopropylphenyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]methanesulfonamide (CAS 908338-43-2)
- Josamycin Propionate - API Standards (CAS 40922-77-8)
- 1,1,1-Trifluoro-N-[(11bR)-4-oxido-2,6-bis[2,4,6-trisisopropylphenyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]methanesulfonamide (CAS 1239466-15-9)
- Ponatinib Impurity 16 (CAS CATO-C4X-226916)
- Carvedilol EP Impurity A (CAS 1198090-73-1)
- Vonoprazan Impurity 125 (CAS CATO-C4X-1020125)
- 2-Methoxy-6-(naphthalen-1-ylmethoxymethyl)-benzoic acid methyl ester (CAS 1171923-66-2)
- Imatinib Impurity 45 (CAS 152460-07-6)
- 2,3-Difluorophenylacetonitrile (CAS 145689-34-5)
- 6-Chloro-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydrochloride (CAS 1260638-90-1)
- (1-(2,5-Dimethylphenyl)ethyl)hydrazine (CAS 1016523-86-6)
- Ixazomib Impurity 4 (CAS CATO-C4X-12674)
- (Asp28)-Exenatide trifluoroacetate salt (CAS 1678417-24-7)
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