Crisaborole Impurity 7 CAS 2803552-55-6
| CAS No. | 2803552-55-6 |
| Molecular Formula | C14H11NO3 |
| Molecular Weight | 241.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Crisaborole Impurity 7 (C14H11NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Crisaborole Impurity 7 (CAS 2803552-55-6) is a certified pharmaceutical impurity reference standard with the molecular formula C14H11NO3 and a molecular weight of 241.24 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Crisaborole Impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H11NO3 |
| Molecular Weight | 241.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 1 |
Related Crisaborole Standards
- Crisaborole lmpurity 87 (CAS CATO-C4X-202187)
- Crisaborole impurity 161 (CAS CATO-C4X-2021161)
- Crisaborole Impurity 8 (CAS CATO-C4X-20218)
- Crisaborole Impurity 64 (CAS 1160182-44-4)
- Crisaborole lmpurity 78 (CAS 2251695-12-0)
- Crisaborole Hydrate Salt (CAS 2760304-92-3)
- Crisaborole Impurity 10 (CAS 906673-42-5)
- Crisaborole Impurity 11 (CAS 943311-54-4)
Recommended Standards
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- Pranoprofen Impurity 80 (CAS CATO-C4X-181180)
- Methocarbamol (CAS 532-03-6)
- Pranoprofen Impurity 43 (CAS CATO-C4X-181143)
- Tadalafil Impurity 152 (CAS CATO-C4X-1087152)
- Atropine EP Impurity B(Noratropine)Hydrate (CAS 16839-98-8(free base))
- Enarodustat Impurity 4 (CAS CATO-C4X-32284)
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- 3-{2-[(2,6-Difluorobenzyl)oxy]ethyl}piperidinehydrochloride (CAS 1219964-54-1)
- Liraglutide Impurity 5 TFA Salt (CAS CATO-C4X-19925)
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