Etrasimod impurity 20 CAS CATO-C4X-321420
| CAS No. | CATO-C4X-321420 |
| Molecular Formula | C22H21NO3 |
| Molecular Weight | 347.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Etrasimod impurity 20.
As a process- or degradation-related impurity, Etrasimod impurity 20 (CAS CATO-C4X-321420, C22H21NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Etrasimod impurity 20 (C22H21NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Etrasimod impurity 20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H21NO3 |
| Molecular Weight | 347.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Etrasimod Standards
- Etrasimod Impurity 73 (CAS CATO-C4X-321473)
- Etrasimod Impurity 31 (CAS 1643842-60-7)
- Etrasimod impurity 15 (CAS CATO-C4X-321415)
- Etrasimod Impurity 46 (CAS CATO-C4X-321446)
- Etrasimod Impurity 65 (CAS CATO-C4X-321465)
- Etrasimod Impurity 66 (CAS CATO-C4X-321466)
- Etrasimod impurity 8 (CAS CATO-C4X-32148)
- Etrasimod Impurity 45 (CAS CATO-C4X-321445)
Recommended Standards
- Isoprenaline Impurity 27 (CAS CATO-C4X-277527)
- Salcaprozate Impurity 7 (CAS CATO-C4X-25077)
- Vonoprazan Impurity N20 (CAS 2416241-98-8)
- Tiotropium impurity 45 (CAS 535995-21-2)
- Tiotropium Bromide Impurity 21 (CAS CATO-C4X-176421)
- Avibactam Impurity 77 (CAS CATO-C4X-134877)
- Tepotinib impurity 27 (CAS CATO-C4X-337427)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com