Glumetinib Impurity 12 CAS CATO-C4X-325912
| CAS No. | CATO-C4X-325912 |
| Molecular Formula | C26H14Br2N10O4S2 |
| Molecular Weight | 754.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Glumetinib Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Glumetinib Impurity 12 (CAS CATO-C4X-325912, C26H14Br2N10O4S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C26H14Br2N10O4S2, Glumetinib Impurity 12 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 754.39 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C26H14Br2N10O4S2 |
| Molecular Weight | 754.39 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 24.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 10 |
| Sulfur Atoms | 2 |
Related Glumetinib Standards
- Glumetinib Impurity 10 (CAS CATO-C4X-325910)
- Glumetinib Impurity 11 (CAS CATO-C4X-325911)
- Glumetinib Impurity 8 (CAS CATO-C4X-32598)
- Glumetinib Impurity 9 (CAS CATO-C4X-32599)
- Glumetinib (CAS 1642581-63-2)
- Glumetinib Impurity 13 (CAS CATO-C4X-325913)
- Glumetinib Impurity 3 (CAS CATO-C4X-32593)
- Glumetinib impurity 1 (CAS CATO-C4X-32591)
Recommended Standards
- 2,6-Dibromo-9,10-bis(9,9-dimethyl-9H-fluoren-2-yl)-9,10-dihydroanthracene-9,10-diol (CAS 1154751-56-0)
- 5’-Iodoresiniferatoxin (CAS 535974-91-5)
- Sn(IV) Mesoporphyrin IX Dichloride (CAS 106344-20-1)
- 6’-Iodoresiniferatoxin (CAS 335151-55-8)
- Sitafloxacin Impurity 27 (CAS CATO-C4X-115527)
- Isavuconazole Impurity 234 (CAS CATO-C4X-1236234)
- Meropenem Impurity 11 (CAS CATO-C4X-130911)
- Lincomycin EP Impurity E (CAS 13380-36-4)
- 4-Fluoro-6-nitroisoquinolin-1-ol (CAS 1508295-22-4)
- (2E)-2-(4-Chlorophenyl)-3-[(2-methoxyphenyl)amino]prop-2-enenitrile (CAS 338402-81-6)
- 3-Amino-1-(3-(trifluoromethyl)phenyl)propan-1-ol (CAS 1447967-06-7)
- N-(4-chlorobenzyl)tetrahydrofuran-3-amine (CAS 1339621-32-7)
- 6-Methoxy-3-methylpyridine-2-carboxaldehyde (CAS 123506-64-9)
- C-telopeptide (CAS 162929-64-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com