Glumetinib impurity 1 CAS CATO-C4X-32591
| CAS No. | CATO-C4X-32591 |
| Molecular Formula | C13H7Br2N5O2S |
| Molecular Weight | 457.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Glumetinib impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Glumetinib impurity 1 (CAS CATO-C4X-32591) is a certified pharmaceutical impurity reference standard with the molecular formula C13H7Br2N5O2S and a molecular weight of 457.10 g/mol.
Based on its molecular formula C13H7Br2N5O2S, Glumetinib impurity 1 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 457.10 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H7Br2N5O2S |
| Molecular Weight | 457.10 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Glumetinib Standards
- Glumetinib Impurity 2 (CAS CATO-C4X-32592)
- Glumetinib Impurity 3 (CAS CATO-C4X-32593)
- Glumetinib (CAS 1642581-63-2)
- Glumetinib Impurity 13 (CAS CATO-C4X-325913)
- Glumetinib Impurity 5 (CAS CATO-C4X-32595)
- Glumetinib Impurity 6 (CAS CATO-C4X-32596)
- Glumetinib Impurity 15 (CAS CATO-C4X-325915)
- Glumetinib Impurity 7 (CAS CATO-C4X-32597)
Recommended Standards
- Gold, [(dimethylamino)phenylmethylene]iodo- (CAS 88682-84-2)
- Benzyl 5-bromo-6-iodo-1H-indazole-1-carboxylate (CAS 2416015-78-4)
- Tributyl(perfluorophenyl)stannane (CAS 1045-56-3)
- (2-Hydroxy-3,5-diiodophenyl)(piperidin-1-yl)methanone (CAS 1007818-06-5)
- Vonoprazan Fumarate Impurity 56 (CAS 445-27-2)
- Voriconazole Impurity 70 (CAS 115617-41-9)
- Nirmatrelvir Impurity 4 (CAS CATO-C4X-28744)
- 5-(4-Bromophenyl)-1H-tetrazole (CAS 50907-23-8)
- 2-Chloro-5-((piperidin-4-yloxy)methyl)pyridine dihydrochloride (CAS 1185312-88-2)
- 2-Isopropoxybutanohydrazide hydrochloride (CAS 1049749-98-5)
- 3-Chloro-N,N-bis(cyanomethyl)benzamide (CAS 54240-91-4)
- N-(4-Nitro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (CAS 1150271-73-0)
- 4-(2-((4-Chlorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)benzoic acid (CAS 338772-46-6)
- Macrocyclic Peptide flaviviridae Viruses InhibitorDISCONTINUED (CAS 1510840-70-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com