Atogepant Impurity 10 CAS CATO-C4X-328510
| CAS No. | CATO-C4X-328510 |
| Molecular Formula | C28H40ClN3O4Si |
| Molecular Weight | 546.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 546.17 g/mol gives Atogepant Impurity 10 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Atogepant Impurity 10 (CAS CATO-C4X-328510), a pharmacopoeial impurity reference standard (molecular formula C28H40ClN3O4Si, MW 546.17 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Atogepant Impurity 10 (C28H40ClN3O4Si) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 546.17 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H40ClN3O4Si |
| Molecular Weight | 546.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Atogepant Standards
- Atogepant Impurity 59 (CAS CATO-C4X-328559)
- Atogepant Impurity 60 (CAS CATO-C4X-328560)
- Atogepant Impurity 61 (CAS CATO-C4X-328561)
- Atogepant Impurity 62 (CAS CATO-C4X-328562)
- Atogepant Impurity 63 (CAS CATO-C4X-328563)
- Atogepant Impurity 64 (CAS CATO-C4X-328564)
- Atogepant Impurity 65 (CAS CATO-C4X-328565)
- Atogepant Impurity 66 (CAS CATO-C4X-328566)
Recommended Standards
- 1-(3,5-Bis(perfluorobutyl)-1H-pyrazol-1-yl)ethan-1-one (CAS 247170-28-1)
- Macitentan Impurity 3 (CAS 1103522-45-7)
- Amiodarone EP Impurity D (CAS 1951-26-4)
- Dotinurad Impurity 262 (CAS CATO-C4X-2494262)
- Desmopressin Impurity 48 (CAS CATO-C4X-221548)
- Sacubitril impurity 15 (CAS CATO-C4X-280915)
- Cefmenoxime Impurity 1 (CAS 184696-69-3)
- 6-O-(D,L-1-Ethoxyethyl)-1,2:4,5-bis-O-(1-methylethylidene) D,L-myo-Inositol (CAS 197848-74-1)
- 4-Chloro-4,4-difluoro-1-(4-fluorophenyl)butane-1,3-dione (CAS 164342-74-9)
- (3-Fluoropiperidin-3-yl)methanol (CAS 1416499-59-6)
- Ac-Asp-Arg-Leu-Asp-Ser-OH (CAS 153959-57-0)
- 7-Fluoro-3-(methoxymethoxy)-8-methylnaphthalen-1-yl trifluoromethanesulfonate (CAS 2791276-54-3)
- 4,4＇-Diaminobenzanilide (CAS 785-30-8)
- Semaglutide impurity 38 (CAS CATO-C4X-222638)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com