Foritinib Impurity 2 CAS CATO-C4X-33102
| CAS No. | CATO-C4X-33102 |
| Molecular Formula | C20H24N2O4 |
| Molecular Weight | 356.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Foritinib Impurity 2 (CAS CATO-C4X-33102, C20H24N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Foritinib Impurity 2 (C20H24N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H24N2O4 |
| Molecular Weight | 356.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Foritinib Standards
- Foritinib Impurity 16 (CAS CATO-C4X-331016)
- Foritinib Impurity 17 (CAS CATO-C4X-331017)
- Foritinib Impurity 13 (CAS CATO-C4X-331013)
- Foritinib Impurity 14 (CAS CATO-C4X-331014)
- Foritinib Impurity 5 (CAS CATO-C4X-33105)
- Foritinib Impurity 9 (CAS CATO-C4X-33109)
- Foritinib Impurity 1 (CAS CATO-C4X-33101)
- Foritinib Impurity 8 (CAS CATO-C4X-33108)
Recommended Standards
- Levodropropizine Impurity 7 (CAS CATO-C4X-23987)
- 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline (CAS 545380-34-5)
- Quinine Sulfate Impurity 5 (CAS 101655-92-9)
- MS-PEG4-t-butyl ester (CAS 1024602-74-1)
- Lapatinib Impurity 10 (CAS 231278-84-5)
- Iopromide impurity 16 (CAS CATO-C4X-183216)
- Tetrabenazine Impurity C298 (CAS 100322-43-8)
- Peramivir impurity 112 (CAS CATO-C4X-1833112)
- 4-Bromo-2-methoxy-6-methylpyridin-3-amine (CAS 2763158-35-4)
- 1-(Tetrahydro-2H-pyran-4-yl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1969279-38-6)
- Benzothiazol-2-yl-piperidin-4-ol (CAS 1011455-82-5)
- 4-((Anthracen-9-ylmethylene)amino)-3-(2-methoxyphenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478256-55-2)
- Chlorodimethyl(pentafluorophenyl)silane (CAS 20082-71-7)
- Semaglutide impurity 60 (CAS CATO-C4X-222660)
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