Capivasertib Impurity 47 CAS CATO-C4X-331247
| CAS No. | CATO-C4X-331247 |
| Molecular Formula | C10H10ClNO2 |
| Molecular Weight | 211.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Capivasertib Impurity 47 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 211.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Capivasertib Impurity 47 (CAS CATO-C4X-331247) is a certified pharmaceutical impurity reference standard with the molecular formula C10H10ClNO2 and a molecular weight of 211.64 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10ClNO2 |
| Molecular Weight | 211.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Capivasertib Standards
- Capivasertib Impurity 40 (CAS CATO-C4X-331240)
- Capivasertib Impurity 23 (CAS CATO-C4X-331223)
- Capivasertib Impurity 39 (CAS CATO-C4X-331239)
- Capivasertib Impurity 45 (CAS CATO-C4X-331245)
- Capivasertib Impurity 18 (CAS CATO-C4X-331218)
- Capivasertib Impurity 17 (CAS CATO-C4X-331217)
- Capivasertib Impurity 26 (CAS CATO-C4X-331226)
- Capivasertib Impurity 13 (CAS CATO-C4X-331213)
Recommended Standards
- Lifitegrast Impurity 109 (CAS CATO-C4X-2409109)
- 6-chloro-N-ethyl-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 100376-75-8)
- Lifitegrast Impurity 108 (CAS CATO-C4X-2409108)
- 4-Chloro-1-((1-methyl-1h-pyrazol-4-yl)methyl)-1,2-dihydro-3h-pyrazol-3-imine (CAS 1004452-03-2)
- Imatinib Impurity 69 (CAS 404577-34-0)
- Erlotinib Impurity 24 (CAS 1624294-38-7)
- Ixazomib Impurity 10 (CAS 667403-46-5)
- Ethyl 2-oxo-3-(quinolin-2-yl)propanoate (CAS 13119-76-1)
- 3-Amino-N-mesityl-2-methylpropanamide hydrochloride (CAS 1827885-61-9)
- 1-(1H-Pyrazol-4-yl)ethan-1-one (hydrochloride) (CAS 1803567-08-9)
- 1-Benzyl 3-(tert-butyl) (S)-tetrahydropyridazine-1,3(2H)-dicarboxylate (CAS 72064-51-8)
- BPOX Impurity 4 (CAS 15833-17-7)
- 2-Oxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 1748-63-6)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
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