Capivasertib Impurity 40 CAS CATO-C4X-331240
| CAS No. | CATO-C4X-331240 |
| Molecular Formula | C10H14ClNO |
| Molecular Weight | 199.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Capivasertib Impurity 40 (CAS CATO-C4X-331240) is a certified pharmaceutical impurity reference standard with the molecular formula C10H14ClNO and a molecular weight of 199.68 g/mol.
Capivasertib Impurity 40 (C10H14ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14ClNO |
| Molecular Weight | 199.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Capivasertib Standards
- Capivasertib Impurity 47 (CAS CATO-C4X-331247)
- Capivasertib Impurity 45 (CAS CATO-C4X-331245)
- Capivasertib Impurity 23 (CAS CATO-C4X-331223)
- Capivasertib Impurity 18 (CAS CATO-C4X-331218)
- Capivasertib Impurity 17 (CAS CATO-C4X-331217)
- Capivasertib Impurity 39 (CAS CATO-C4X-331239)
- Capivasertib Impurity 26 (CAS CATO-C4X-331226)
- Capivasertib Impurity 13 (CAS CATO-C4X-331213)
Recommended Standards
- Mianserin Impurity 68 (CAS CATO-C4X-136968)
- Dipropylsulfamoylchloride (CAS 10539-95-4)
- 2857AF 90945-06-5 C10H14ClNO [3-(4-Chloro-phenoxy)-propyl]-methyl-amine (CAS 90945-06-5)
- Sec-butyl(ethyl)sulfamoyl chloride (CAS 1095075-62-9)
- Fexofenadine Impurity N22 (CAS 169032-11-5)
- Flumazenil Impurity 10 (CAS 162110-24-9)
- Zolpidem EP Impurity D (CAS 836627-56-6)
- Blonanserin Impurity 27 (CAS 1648791-23-4)
- Tert-butyl (7-fluoroquinolin-4-yl)carbamate (CAS 1447607-36-4)
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- Tetraphenylphosphonium thiocyanate (CAS 35171-64-3)
- 2-Methoxy-3-(pyridin-4-yl)-6-(trifluoromethyl)pyridine (CAS 1214336-08-9)
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- Tirzepatide Impurity 13 (CAS CATO-C4X-324013)
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