Ledipasvir Impurity 43 CAS CATO-C4X-331343
| CAS No. | CATO-C4X-331343 |
| Molecular Formula | C27H28BrN3O2 |
| Molecular Weight | 506.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ledipasvir Impurity 43 (CAS CATO-C4X-331343), a pharmacopoeial impurity reference standard (molecular formula C27H28BrN3O2, MW 506.43 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ledipasvir Impurity 43 (C27H28BrN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ledipasvir Impurity 43 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H28BrN3O2 |
| Molecular Weight | 506.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Ledipasvir Standards
- Ledipasvir Impurity 48 (CAS CATO-C4X-331348)
- Ledipasvir Impurity 7 (CAS 1441670-89-8)
- Ledipasvir Impurity 26 (CAS CATO-C4X-331326)
- Ledipasvir Impurity 38 (CAS CATO-C4X-331338)
- Ledipasvir Impurity 58 (CAS CATO-C4X-331358)
- Ledipasvir Impurity 27 (CAS CATO-C4X-331327)
- Ledipasvir Impurity 28 (CAS CATO-C4X-331328)
- Ledipasvir Impurity 4 (CAS CATO-C4X-33134)
Recommended Standards
- Apalutamide Impurity 68 (CAS CATO-C4X-274968)
- 4-((2,3-Dichlorophenyl)thio)-1-(4-methoxyphenyl)-2-phenyl-6,7-dihydro-1H-indole-5-carbaldehyde (CAS 477869-32-2)
- Landiolol Impurity 97 (CAS CATO-C4X-262197)
- (2S,3R,4R,5R)-4-(((2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,5,6-pentaol (CAS 61473-64-1)
- Difelikefalin Impurity 81 (CAS CATO-C4X-304181)
- Linagliptin impurity 151 (CAS CATO-C4X-1101151)
- Avatrombopag Impurity 82 (CAS CATO-C4X-223482)
- Ethyl (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosa-6,9,12,15,18,21-hexaenoate (CAS 2435680-90-1)
- 2-{[4-(chloromethyl)-1,3-thiazol-2-yl]methyl}-2,3-dihydro-1h-isoindole-1,3-dione (CAS 857549-83-8)
- 4'-(Dimethylamino)biphenyl-3-carboxylic acid (CAS 893737-65-0)
- 4-(2-Methyl-3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carbonyl)phenyl N-methylcarbamate (CAS 1009235-34-0)
- Octyl dihydrogen phosphate (CAS 3991-73-9)
- 2-[5-acetyl-3-(methoxycarbonyl)-4-methyl-1h-pyrrol-2-yl]acetic acid (CAS 867329-95-1)
- Tetrapeptide-30/Tegopep (CAS 1036207-61-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com