Avatrombopag Impurity 82 CAS CATO-C4X-223482
| CAS No. | CATO-C4X-223482 |
| Molecular Formula | C21H19Cl3N4O3S2 |
| Molecular Weight | 545.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Avatrombopag Impurity 82 (C21H19Cl3N4O3S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 545.89 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Avatrombopag Impurity 82 (CAS CATO-C4X-223482, C21H19Cl3N4O3S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Avatrombopag Impurity 82 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H19Cl3N4O3S2 |
| Molecular Weight | 545.89 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag Impurity 12 (CAS 762237-66-1)
- Avatrombopag Impurity 141 (CAS 570403-05-3)
- Avatrombopag Impurity 62 (CAS 570403-04-2)
- Avatrombopag Impurity 101 (CAS CATO-C4X-2234101)
- Avatrombopag Impurity 1 (CAS 2626934-45-8)
- Avatrombopag impurity 133 (CAS CATO-C4X-2234133)
- Avatrombopag Impurity 7 (CAS CATO-C4X-22347)
- Avatrombopag Impurity 83 (CAS CATO-C4X-223483)
Recommended Standards
- 2,2',2'',5'-Tetrabromo-1,1':4',1''-terphenyl (CAS 912922-58-8)
- (5E)-1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-5-{[(4-phenoxyphenyl)amino]methylidene}-1,3-diazinane-2,4,6-trione (CAS 339101-11-0)
- Fingolimod Palmitate Amide (CAS 1242271-26-6)
- (2S)-isopropyl2-(((((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate (CAS 1496551-77-9)
- Topiroxostat Impurity 11 (CAS CATO-C4X-105511)
- Atogepant Impurity 78 (CAS 1488326-89-1)
- Travoprost Impurity 51 (CAS CATO-C4X-192551)
- 1-(Methylamino)-3-(1h-1,2,4-triazol-1-yl)cyclohexane-1-carboxamide (CAS 1508535-64-5)
- (3-Aminopropyl)(difluoromethyl)phosphinic acid (CAS 133345-73-0)
- 2-Aminohex-5-ynamide (CAS 763075-22-5)
- 3-((7-Chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-yl)amino)propan-1-ol (CAS 372975-34-3)
- 4-(5-aminopentylamino)-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione (CAS 2093386-39-9)
- (R)-7-Fluorochroman-4-ol (CAS 1270296-57-5)
- D-[Asp]9-Semaglutide (CAS CATO-CPTD788631)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com