Ledipasvir Impurity 3 CAS CATO-C4X-33136
| CAS No. | CATO-C4X-33136 |
| Molecular Formula | C5H8Br2 |
| Molecular Weight | 227.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Ledipasvir Impurity 3 (CAS CATO-C4X-33136, C5H8Br2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ledipasvir Impurity 3 (C5H8Br2) is characterized by bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Ledipasvir Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H8Br2 |
| Molecular Weight | 227.93 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| Halogen Content | Br-containing |
Related Ledipasvir Standards
- Ledipasvir Impurity 51 (CAS CATO-C4X-331351)
- Ledipasvir Impurity 33 (CAS CATO-C4X-331333)
- Ledipasvir impurity 1 (CAS 134877-62-6)
- Ledipasvir Impurity 3 (CAS CATO-C4X-33133)
- Ledipasvir Impurity 12 (CAS CATO-C4X-331312)
- Ledipasvir Impurity 7 (CAS CATO-C4X-33137)
- Ledipasvir Impurity 34 (CAS CATO-C4X-331334)
- Ledipasvir Impurity 8 (CAS CATO-C4X-33138)
Recommended Standards
- 1,5-dibromopent-2-ene (CAS 58673-29-3)
- periodic acid (CAS 10450-60-9)
- 3-(4,6-dichloro-1,3,5-triazin-2-yl)-1-phenylindole 3-[4,6-bis(chloranyl)-1,3,5-triazin-2-yl]-1-phenyl-indole 354-41-6 A822808 (CAS 354-41-6)
- [5-hydroxy-2-(trifluoromethoxy)phenyl]boronic acid (CAS 1217500-69-0)
- Sildenafil Impurity 87 (CAS CATO-C4X-112887)
- Orforglipron Impurity 89 (CAS CATO-C4X-323489)
- Lafutidine Impurity 13 (CAS 163802-30-0)
- [2-(difluoromethoxy)-5-methoxyphenyl]methanamine (CAS 1094792-05-8)
- (R)-3-(Benzyloxy)-2-hydroxypropanoic Acid (CAS 130111-08-9)
- Methyl 4-fluoro-3-oxopentanoate (CAS 227183-98-4)
- Ethyl 3-(4-formylphenoxy)propanoate (CAS 1099614-15-9)
- Liothyronine EP Impurity A (CAS 51-48-9)
- 3-Methoxy-4-(2-oxo-2-((p-tolylamino)oxy)ethoxy)benzaldehyde (CAS 881586-68-1)
- Tirzepatide Impurity 15 (CAS CATO-C4X-324015)
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