Valbenazine Impurity 3 CAS CATO-C4X-33423
| CAS No. | CATO-C4X-33423 |
| Molecular Formula | C24H38N2O5 |
| Molecular Weight | 434.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 434.57 g/mol gives Valbenazine Impurity 3 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Valbenazine Impurity 3 (CAS CATO-C4X-33423), a pharmacopoeial impurity reference standard (molecular formula C24H38N2O5, MW 434.57 g/mol) used for the identification and quantification of trace impurities in APIs.
Valbenazine Impurity 3 (C24H38N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H38N2O5 |
| Molecular Weight | 434.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ＞95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Valbenazine Standards
- Valbenazine Impurity 1 (CAS 2237934-70-0)
- Valbenazine Impurity 2 (CAS CATO-C4X-33422)
- Valbenazine Impurity 5 (CAS 2624055-87-2)
- Valbenazine (CAS 1025504-45-3)
- Valbenazine Impurity 4 (CAS 1025504-59-9)
- Valbenazine Impurity 7 (CAS CATO-C4X-33427)
- Valbenazine Impurity 8 (CAS CATO-C4X-33428)
- Valbenazine Impurity 6 (CAS CATO-C4X-33426)
Recommended Standards
- N-(3-((5-Cyclopropyl-2-((2-methyl-1,2,3,4-tetrahydroisoquinolin-6-yl)amino)pyrimidin-4-yl)amino)propyl)cyclobutanecarboxamide (CAS 1190379-70-4)
- (S)-N-(2-(4-(tert-Butyl)-1-phenyl-4,5-dihydro-1H-imidazol-2-yl)phenyl)-2-methylquinolin-8-amine (CAS 2260565-00-0)
- MDMB-CHMCZCA (CAS 2219324-32-8)
- 2-((4-(Piperazin-1-yl)phenyl)amino)-N-(1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl)pyrimidine-4-carboxamide (CAS 943122-71-2)
- Venetoclax Impurity 95 (CAS CATO-C4X-249595)
- Bumetanide Impurity 32 (CAS 22892-95-1)
- Alfuzosin EP Impurity C (CAS 98902-34-2)
- 1-tert-Butyl 4-methyl 4-propylpiperidine-1,4-dicarboxylate (CAS 1306738-94-2)
- (3-Bromophenyl)(4-ethylphenyl)methanol (CAS 333360-85-3)
- Cefepime Impurity 30 (CAS CATO-C4X-119330)
- 1-Bromo-3-methyloctane (CAS 56608-78-7)
- Methyl 2-methyl-1H-imidazole-1-carboxylate (CAS 74061-51-1)
- 2-(Aminomethyl)-6-(difluoromethyl)pyridine-4-sulfonyl chloride (CAS 1805304-23-7)
- [y-Glu15]-Semaglutide Impurity 134 (CAS CATO-C4X-2226134)
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