Valbenazine Impurity 4 CAS 1025504-59-9
| CAS No. | 1025504-59-9 |
| Molecular Formula | C24H38N2O4 |
| Molecular Weight | 418.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Valbenazine Impurity 4.
CATO supplies Valbenazine Impurity 4 (CAS 1025504-59-9), a pharmacopoeial impurity reference standard (molecular formula C24H38N2O4, MW 418.57 g/mol) used for the identification and quantification of trace impurities in APIs.
Valbenazine Impurity 4 (C24H38N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H38N2O4 |
| Molecular Weight | 418.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Valbenazine Standards
- Valbenazine (CAS 1025504-45-3)
- Valbenazine Impurity 7 (CAS CATO-C4X-33427)
- Valbenazine Impurity 8 (CAS CATO-C4X-33428)
- Valbenazine Impurity 5 (CAS 2624055-87-2)
- Valbenazine Impurity 6 (CAS CATO-C4X-33426)
- Valbenazine Impurity 1 (CAS 2237934-70-0)
- Valbenazine Impurity 2 (CAS CATO-C4X-33422)
- Valbenazine Impurity 3 (CAS CATO-C4X-33423)
Recommended Standards
- Treprostinil Ethyl Ester (CAS 1355990-07-6)
- 2-Nor Latanoprost (CAS CATO-C4X-19414)
- Cinnarizine EP Impurity E (CAS 216581-01-0)
- Simvastatin (CAS 79902-63-9)
- Posaconazole Impurity 60 (CAS CATO-C4X-120860)
- Lenvatinib Impurity 102 (CAS 15568-85-1)
- Olodaterol impurity 36 (CAS CATO-C4X-194336)
- 3-(trimethylazaniumyl)propane-1-sulfonate (CAS 21865-17-8)
- 3-Methoxy-5-(5-methyl-1H-tetrazol-1-yl)aniline (CAS 799262-39-8)
- 2-(((2,3-Dimethylbutan-2-yl)dimethylsilyl)oxy)ethanol (CAS 855788-01-1)
- Cyclopentanecarbonyl Chloride (CAS 4524-93-0)
- (2E)-3-[(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)amino]-2-cyanobut-2-enamide (CAS 303153-06-2)
- 401640-94-6 2-Bromo-N-(4-nitrophenyl)butanamide MFCD03014456 (CAS 401640-94-6)
- Xenopsin-Related Peptide 2 (XP-2) (H-9340.0005) (CAS 117442-29-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com