Dosulepin N-Oxide Sulfoxide hydrochloride CAS CATO-C4X-33561
| CAS No. | CATO-C4X-33561 |
| Molecular Formula | C19H21NO2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Dosulepin N-Oxide Sulfoxide hydrochloride (CAS CATO-C4X-33561), a pharmacopoeial impurity reference standard (molecular formula C19H21NO2SHCl, MW 363.90 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Dosulepin N-Oxide Sulfoxide hydrochloride (C19H21NO2SHCl) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Dosulepin N-Oxide Sulfoxide hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H21NO2S HCl |
| Molecular Weight | 363.90 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dosulepin Standards
- Dosulepin EP Impurity A (CAS 1447-71-8)
- Dosulepin EP Impurity B (CAS 1531-77-7)
- Dosulepin EP Impurity C (CAS 1531-85-7)
- Dosulepin EP Impurity E (CAS 25627-38-7)
- Dosulepin Hydrochloride - Impurity E (Hydrochloride Salt) (CAS 25627-39-8)
- Dosulepin EP Impurity D (CAS 25846-81-5)
- Dosulepin Sulfone (CAS 33301-24-5)
- Dosulepin Impurity A (CAS 42046-35-5)
Recommended Standards
- Ruxolitinib Impurity 121 (CAS CATO-C4X-2058121)
- Palbociclib Impurity 124 (CAS CATO-C4X-1125124)
- Upadacitinib Impurity 181 (CAS CATO-C4X-2405181)
- 2-(Hydroxymethyl)-1,3-thiazole-4-carboxaldehyde (CAS 774239-03-1)
- 2,2,2-Trifluoro-N-(2-methoxyquinolin-5-yl)acetamide (CAS 77738-86-4)
- Methyl 6-fluoro-1H-pyrrolo[3,2-b]pyridine-3-carboxylate (CAS 2231676-04-1)
- 5-chloroindole (CAS 17422-32-1)
- 5-Amino-1-(4-isopropylphenyl)-1H-pyrazole-4-carbonitrile (CAS 1175899-74-7)
- α-Amino-2-furanacetonitrile (CAS 62626-61-3)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com