Ammoxetine Impurity 17 CAS CATO-C4X-335717
| CAS No. | CATO-C4X-335717 |
| Molecular Formula | C14H10F2O4 |
| Molecular Weight | 280.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Ammoxetine Impurity 17 (CAS CATO-C4X-335717, C14H10F2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ammoxetine Impurity 17 (C14H10F2O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C14H10F2O4 |
| Molecular Weight | 280.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Ammoxetine Standards
- Ammoxetine Impurity 18 (CAS CATO-C4X-335718)
- Ammoxetine Impurity 20 (CAS CATO-C4X-335720)
- Ammoxetine Impurity 22 (CAS CATO-C4X-335722)
- Ammoxetine Impurity 1 (CAS CATO-C4X-33571)
- Ammoxetine Impurity 13 (CAS CATO-C4X-335713)
- Ammoxetine Impurity 4 (CAS CATO-C4X-33574)
- Ammoxetine Impurity 3 (CAS CATO-C4X-33573)
- Ammoxetine Impurity 5 (CAS CATO-C4X-33575)
Recommended Standards
- Methyl 2-fluoro-3-isopropoxy-5-(trifluoromethyl)benzoate (CAS 2586126-15-8)
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- 4,5,6,7-Tetrafluoro-3-methyl-1-phenyl-1H-indazole (CAS 84409-38-1)
- Levonorgestrel Impurity 40 (10R) (CAS CATO-C4X-167740)
- Dapagliflozin dibromide impurity (CAS 1043252-56-7)
- Olaparib Impurity 42 (CAS CATO-C4X-113542)
- Bempedoic Acid Intermediate Impurity 14 d4 (CAS 2408132-01-2)
- 7,7-Dimethoxy-1-(phenylthio)octahydroindolizine (CAS 62240-38-4)
- 3-(2-Chloropropanoyl)-1-(2-methylpropyl)urea (CAS 923106-33-6)
- Ketoprofen Impurity 38 (CAS 64379-72-2)
- 2-(Cyclopentylthio)-5-phenyl-1-(p-tolyl)-1H-imidazole (CAS 1207011-95-7)
- 4-(((1H-Indol-3-yl)methylene)amino)-9-methoxy-7H-furo[3,2-g]chromen-7-one (CAS 78439-81-3)
- Des-[Gly]31-Semaglutide(x TFA Salt) (CAS 873874-39-6(free base))
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