Ammoxetine Impurity 3 CAS CATO-C4X-33573
| CAS No. | CATO-C4X-33573 |
| Molecular Formula | C8H7Br2FO2 |
| Molecular Weight | 313.95 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ammoxetine Impurity 3.
Ammoxetine Impurity 3 (CAS CATO-C4X-33573) is a certified pharmaceutical impurity reference standard with the molecular formula C8H7Br2FO2 and a molecular weight of 313.95 g/mol.
Ammoxetine Impurity 3 (C8H7Br2FO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ammoxetine Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7Br2FO2 |
| Molecular Weight | 313.95 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ＞95% |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Br-containing |
Related Ammoxetine Standards
- Ammoxetine Impurity 21 (CAS CATO-C4X-335721)
- Ammoxetine Impurity 20 (CAS CATO-C4X-335720)
- Ammoxetine Impurity 22 (CAS CATO-C4X-335722)
- Ammoxetine Impurity 17 (CAS CATO-C4X-335717)
- Ammoxetine Impurity 18 (CAS CATO-C4X-335718)
- Ammoxetine Impurity 1 (CAS CATO-C4X-33571)
- Ammoxetine Impurity 13 (CAS CATO-C4X-335713)
- Ammoxetine Impurity 4 (CAS CATO-C4X-33574)
Recommended Standards
- 1,5-Dibromo-3-fluoro-2-(methoxymethoxy)benzene (CAS 2379322-34-4)
- 5,6'-Dibromo-2,2'-bipyridine (CAS 1042150-70-8)
- 1,3-Dibromo-5-fluoro-2-(methoxymethoxy)benzene (CAS 2244107-73-9)
- 5-Bromo-2-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1073353-75-9)
- Atrasentan Impurity 22 (CAS 1058393-00-2)
- Eravacycline impurity 21 (CAS CATO-C4X-293821)
- Exatecan Impurity 3 Methanesulfonate (CAS 2938875-39-7；2489613-15-0（free base）)
- Methyl 2-[4-phenyl-2-(pyridin-2-yl)-1,3-thiazol-5-yl]acetate (CAS 861209-68-9)
- 3-(tert-Butyl)-2,4-dimethyl-1H-pyrrole (CAS 28991-99-3)
- 8-Methyl-1h,2h,3h,4h,9h-pyrido[3,4-b]indole (CAS 23046-74-4)
- Norfloxacin Impurity 36 (CAS CATO-C4X-146836)
- (2-Amino-3-(difluoromethyl)-5-methoxypyridin-4-yl)methanol (CAS 1805970-53-9)
- Ethyl 2-(5,6,7,8-tetrahydroquinolin-5-yl)acetate (CAS 62741-61-1)
- Insulin Lispro (CAS 133107-64-9)
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