Olaparib Impurity 42 CAS CATO-C4X-113542
| CAS No. | CATO-C4X-113542 |
| Molecular Formula | C16H8FNO2 |
| Molecular Weight | 265.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 265.24 g/mol gives Olaparib Impurity 42 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Olaparib Impurity 42 (CAS CATO-C4X-113542), a pharmacopoeial impurity reference standard (molecular formula C16H8FNO2, MW 265.24 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C16H8FNO2, Olaparib Impurity 42 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 265.24 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Olaparib Impurity 42 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H8FNO2 |
| Molecular Weight | 265.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Olaparib Standards
- Olaparib Impurity 131 (CAS CATO-C4X-1135131)
- Olaparib Impurity 132 (CAS CATO-C4X-1135132)
- Olaparib Impurity 133 (CAS CATO-C4X-1135133)
- Olaparib impurity 142 (CAS CATO-C4X-1135142)
- Olaparib Impurity 41 (CAS 763114-25-6)
- Olaparib Impurity 130 (CAS CATO-C4X-1135130)
- Olaparib Impurity 19 (CAS CATO-C4X-113519)
- Olaparib Impurity 115 (CAS CATO-C4X-1135115)
Recommended Standards
- Avibactam Impurity 54 (CAS 1383913-01-6)
- Avibactam Impurity 81 (CAS CATO-C4X-134881)
- Avibactam impurity 92 (CAS CATO-C4X-134892)
- Carbadox-d3 (CAS 1185240-06-5)
- Enzalutamide Impurity 44 (CAS 24115-24-0)
- Revefenacin Impurity 13 (CAS 864760-28-1)
- Flunarizine impurity 50 (CAS CATO-C4X-135750)
- ethyl 6-(trifluoromethyl)pyridazine-3-carboxylate (CAS 1192155-06-8)
- 4-(2-Methyl-2-phenylhydrazinyl)-5,6-dihydropyridin-2(1H)-one (CAS 139122-76-2)
- H-Ile-OAll.TosOH (CAS 88224-05-9)
- Methyl 4-(4-methylphenyl)-2,4-dioxobutanoate (CAS 39757-29-4)
- 2-((1-Acetylpiperidin-4-yl)(isopropyl)amino)acetic acid (CAS 1353963-66-2)
- 2-Hydroxy-5-methyl-3-sulfamoylbenzoic acid (CAS 926193-62-6)
- Lixisenatide (CAS 320367-13-3（free base）)
Why CATO?
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