Tepotinib impurity 6 CAS CATO-C4X-33746
| CAS No. | CATO-C4X-33746 |
| Molecular Formula | C33H38N6O3 |
| Molecular Weight | 566.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Tepotinib impurity 6 (CAS CATO-C4X-33746, C33H38N6O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Tepotinib impurity 6 (C33H38N6O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tepotinib impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C33H38N6O3 |
| Molecular Weight | 566.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Tepotinib Standards
- Tepotinib impurity 1 (CAS 1103506-80-4)
- Tepotinib impurity 25 (CAS CATO-C4X-337425)
- Tepotinib impurity 24 (CAS CATO-C4X-337424)
- Tepotinib impurity 8 (CAS CATO-C4X-33748)
- Tepotinib impurity 5 (CAS 1233361-38-0)
- Tepotinib impurity 2 (CAS 1233361-36-8)
- Tepotinib impurity 15 (CAS CATO-C4X-337415)
- Tepotinib Impurity 36 (CAS 1103507-25-0)
Recommended Standards
- Ritonavir EP Impurity D (CAS 144142-33-6)
- H-D-Phe-D-Phe -D-Lys-γ-Pip-OH (CAS CATO-CPTD788707)
- Formoterol impurity 146 (CAS CATO-C4X-1525146)
- H-D-Phe-L-Phe-D-Lys-γ-Pip-OH (CAS CATO-CPTD788742)
- Ticagrelor impurity 161 (CAS 1157692-93-7)
- Cefoperazone Impurity 41 (CAS CATO-C4X-114941)
- Hydrocortisone Impurity 55 (CAS CATO-C4X-140155)
- 1,1,3,5,6-Pentachloro-1,2,2,3,4,4,5,6,6-nonafluorohexane (CAS 307-26-6)
- 2-(4-Methoxypyridin-2-yl)propan-2-amine (CAS 1516232-83-9)
- (4-(4-Chlorophenyl)pyrrolidin-3-yl)methanol (CAS 55438-52-3)
- N-(Cyclopentylmethyl)-2,3-dihydrobenzofuran-6-amine (CAS 61070-38-0)
- tert-Butyl 4-Bromophenethyl(ethyl)carbamate (CAS 2386114-04-9)
- Trimebutine impurity 23 (CAS CATO-C4X-185823)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
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