Momelotinib impurity 3 CAS CATO-C4X-33773
| CAS No. | CATO-C4X-33773 |
| Molecular Formula | C23H23N5O4 |
| Molecular Weight | 433.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Momelotinib impurity 3 (CAS CATO-C4X-33773, C23H23N5O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Momelotinib impurity 3 (C23H23N5O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Momelotinib impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H23N5O4 |
| Molecular Weight | 433.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Momelotinib Standards
- Momelotinib impurity 2 (CAS CATO-C4X-33772)
- Momelotinib impurity 7 (CAS 1841094-23-2)
- Momelotinib impurity 9 (CAS CATO-C4X-33779)
- Momelotinib (CAS 1056634-68-4)
- Momelotinib impurity 8 (CAS CATO-C4X-33778)
- Momelotinib impurity 11 (CAS CATO-C4X-337711)
- Momelotinib impurity 6 (CAS CATO-C4X-33776)
- Momelotinib impurity 13 (CAS 1241667-95-7)
Recommended Standards
- Pemafibrate Impurity 84 (CAS CATO-C4X-290384)
- 2-Hydroxypropyl Nortadalafil (Mixture of Diastereomers) (CAS 1353020-85-5)
- N-Nitroso Ozanimod (CAS CATO-C4X-29023)
- Meleagrin (CAS 71751-77-4)
- Amidotrizoate EP Impurity A (CAS 1713-07-1)
- Vortioxetine Impurity 8 (CAS 13616-83-6)
- Abemaciclib Impurity 16 DiTrifluoroacetate (CAS CATO-C4X-293716)
- 5-Bromo-2-(thiazolidin-3-yl)nitrobenzene (CAS 1774894-47-1)
- (S)-1-(diphenylphosphanyl)propan-2-amine hydrochloride (CAS 74192-91-9)
- 1-(4-Butoxy-3-methoxyphenyl)ethan-1-ol (CAS 1156390-14-5)
- Sunitinib Impurity 38 (CAS CATO-C4X-133338)
- 2-(4-Ethylbenzoyl)-6-methoxypyridine (CAS 1187167-93-6)
- N,N'-(4,6-Dichloropyrimidine-2,5-diyl)diformamide (CAS 116477-30-6)
- MCH-Gene-Overprinted-Polypeptide-14 (rat) (H-4746.0500) (CAS 182917-44-8)
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