Momelotinib impurity 8 CAS CATO-C4X-33778
| CAS No. | CATO-C4X-33778 |
| Molecular Formula | C23H22N6O2 |
| Molecular Weight | 414.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Momelotinib impurity 8 (C23H22N6O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Momelotinib impurity 8 (CAS CATO-C4X-33778) is a certified pharmaceutical impurity reference standard with the molecular formula C23H22N6O2 and a molecular weight of 414.46 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Momelotinib impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H22N6O2 |
| Molecular Weight | 414.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Momelotinib Standards
- Momelotinib (CAS 1056634-68-4)
- Momelotinib impurity 7 (CAS 1841094-23-2)
- Momelotinib impurity 2 (CAS CATO-C4X-33772)
- Momelotinib impurity 3 (CAS CATO-C4X-33773)
- Momelotinib impurity 6 (CAS CATO-C4X-33776)
- Momelotinib impurity 9 (CAS CATO-C4X-33779)
- Momelotinib impurity 13 (CAS 1241667-95-7)
- Momelotinib impurity 1 (CAS CATO-C4X-33771)
Recommended Standards
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- CAS CATO-C4X-34215 (CAS CATO-C4X-34215)
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- Barloxavir impurity 81 (CAS 2814504-20-4)
- Pemafibrate Impurity 33 (CAS 2793549-90-1)
- 8-Methyl-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid (CAS 90771-19-0)
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- 3-(4-Ethoxyphenyl)-3-oxopropanal (CAS 1019024-50-0)
- 4-Sulfanylcyclohexane-1-carboxylic acid (CAS 82001-54-5)
- Tau Peptide (245-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 1428134-39-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com