Momelotinib impurity 7 CAS 1841094-23-2
| CAS No. | 1841094-23-2 |
| Molecular Formula | C23H20N6O3 |
| Molecular Weight | 428.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 428.44 g/mol gives Momelotinib impurity 7 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Momelotinib impurity 7 (CAS 1841094-23-2) is a certified pharmaceutical impurity reference standard with the molecular formula C23H20N6O3 and a molecular weight of 428.44 g/mol.
Based on its molecular formula C23H20N6O3, Momelotinib impurity 7 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 428.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Momelotinib impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H20N6O3 |
| Molecular Weight | 428.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 6 |
Related Momelotinib Standards
- Momelotinib impurity 2 (CAS CATO-C4X-33772)
- Momelotinib impurity 3 (CAS CATO-C4X-33773)
- Momelotinib (CAS 1056634-68-4)
- Momelotinib impurity 8 (CAS CATO-C4X-33778)
- Momelotinib impurity 9 (CAS CATO-C4X-33779)
- Momelotinib impurity 11 (CAS CATO-C4X-337711)
- Momelotinib impurity 6 (CAS CATO-C4X-33776)
- Momelotinib impurity 13 (CAS 1241667-95-7)
Recommended Standards
- Finerenone Impurity 175 (CAS CATO-C4X-2880175)
- Hydroxylysylpyridinoline (CAS CATO-CCFD201971)
- Ozenoxacin Impurity 58 (CAS CATO-C4X-279658)
- Fmoc-p-azido-Phe-OH (CAS 163217-43-4)
- Resmetirom impurity 94 (CAS CATO-C4X-291294)
- Apixaban Impurity 160 (CAS CATO-C4X-1088160)
- Brinzolamide Impurity 15 (CAS 165117-54-4)
- 2-[(1-Boc-4-piperidyl)oxy]ethanamine (CAS 442126-36-5)
- 4,5-Dibromo-2-isopropyl-1H-imidazole (CAS 885266-63-7)
- 2,4,6,7-Tetramethylquinoline (CAS 72681-40-4)
- Trazodone Impurity 96 (CAS CATO-C4X-177296)
- Cyclo(-Phe-Ser) (CAS 35591-00-5)
- 2-(2-isothiocyanatoethyl)pyridine (CAS 36810-91-0)
- Casein kinase II peptide Substrate (CAS 154444-98-1)
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