Nerandomilast impurity 27 CAS CATO-C4X-347327

Description

Compared with other compounds in its class, the molecular weight of 188.63 g/mol gives Nerandomilast impurity 27 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Nerandomilast impurity 27 (CAS CATO-C4X-347327) is a certified pharmaceutical impurity reference standard with the molecular formula C6H5ClN2OS and a molecular weight of 188.63 g/mol.

The molecular framework of Nerandomilast impurity 27 (C6H5ClN2OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Nerandomilast impurity 27 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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