Henagliflozin Impurity 1 CAS CATO-C4X-34811
| CAS No. | CATO-C4X-34811 |
| Molecular Formula | C23H26ClFO6S |
| Molecular Weight | 484.97 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Henagliflozin Impurity 1.
Henagliflozin Impurity 1 (CAS CATO-C4X-34811) is a certified pharmaceutical impurity reference standard with the molecular formula C23H26ClFO6S and a molecular weight of 484.97 g/mol.
Owing to a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Henagliflozin Impurity 1 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 484.97 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Henagliflozin Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H26ClFO6S |
| Molecular Weight | 484.97 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Recommended Standards
- Mometasone Furoate EP Impurity D (CAS 83881-09-8)
- GLPG 0974 (CAS 1391076-61-1)
- Mometasone Furoate EP Impurity C (CAS 1305334-31-9)
- (5E)-3-(2-Chlorophenyl)-5-{[2-nitro-5-(phenylsulfanyl)phenyl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 298216-07-6)
- Nabumetone Impurity 20 (CAS 2960-93-2)
- Vancomycin EP Impurity F (CAS 2415254-43-0)
- Ebastine Impurity 15 (CAS CATO-C4X-202915)
- 1-((3,4-Dimethoxyphenyl)sulfonyl)-3,5-dimethylpiperazine (CAS 1263378-98-8)
- N-[3-(4-methoxy-phenoxy)-propyl]-phthalimide (CAS 100840-46-8)
- 6-Methoxy-3H-spiro[isobenzofuran-1,4'-piperidine] hydrochloride (CAS 1707575-98-1)
- Peracetic Acid Solution (CAS 79-21-0)
- EMImPF6 (CAS 155371-19-0)
- 1,3,5-Trimethyl-1,3,5-Triazinane-2,4,6-Trione (CAS 827-16-7)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
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