Cetirizine EP Impurity B CAS 1000690-91-4
| CAS No. | 1000690-91-4 |
| Molecular Formula | C19H21ClN2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Cetirizine EP Impurity B (CAS 1000690-91-4), a pharmacopoeial impurity reference standard (molecular formula C19H21ClN2O2HCl, MW 381.30 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Cetirizine EP Impurity B is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 381.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Cetirizine EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H21ClN2O2 2*HCl |
| Molecular Weight | 381.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Cetirizine Standards
- Cetirizine Impurity 10 (CAS 1016-78-0)
- rac Cetirizine N-Oxide (Mixture of Diastereomers) (CAS 1076199-80-8)
- Cetirizine USP Related Compound B (CAS 108983-83-1)
- Cetirizine EP Impurity G (CAS 109806-71-5)
- (R)-Cetirizine-d4 Dihydrochloride (CAS 1133210-23-7)
- Cetirizine Impurity N19 (CAS 113740-61-7)
- rac Cetirizine-d8 N-Oxide (CAS 1216444-13-1)
- (±)-Cetirizine-d4 (ethoxy-d4) (CAS 1219803-84-5)
Recommended Standards
- Eltrombopag Impurity 112 (CAS CATO-C4X-1198112)
- Cloperastine Impurity 4 HCl (CAS CATO-C4X-15954)
- Riociguat Impurity 26 (CAS 304874-06-4)
- 1H-Indene-1,2,3-trione (CAS 938-24-9)
- 2-(tert-Butoxy)-5-cyclopropoxypyridine-4-sulfonamide (CAS 1243394-78-6)
- Tetracycline Impurity 9 (CAS CATO-C4X-23319)
- (Prop-2-en-1-yl)[(2,3,4-trimethoxyphenyl)methyl]amine hydrochloride (CAS 1158320-84-3)
- 4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(2-carboxyethyl)heptanedioic acid (CAS 798576-99-5)
- 4-Iodo-3-methoxyisothiazole (CAS 60666-89-9)
- GnRH Associated Peptide (GAP) (1-13), human (CAS 100111-07-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com