Cloperastine Impurity 4 HCl CAS CATO-C4X-15954
| CAS No. | CATO-C4X-15954 |
| Molecular Formula | C20H24ClNO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Cloperastine Impurity 4 HCl (C20H24ClNOHCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 366.33 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Cloperastine Impurity 4 HCl (CAS CATO-C4X-15954, C20H24ClNOHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H24ClNO HCl |
| Molecular Weight | 366.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Cloperastine Standards
- Cloperastine impurity 8 (CAS 132301-89-4)
- (R)-Cloperastine (CAS 132301-91-8)
- Cloperastine Hydrochloride (CAS 14984-68-0)
- (S)-Cloperastine Fendizoate (Levocloperastine Fendizoate) (CAS 220329-19-1)
- Cloperastine (CAS 3703-76-2)
- Cloperastine Impurity 2 (CAS 4960-10-5)
- Cloperastine Impurity 1 (CAS 5630-78-4)
- Cloperastine Impurity 3 (CAS 6954-45-6)
Recommended Standards
- Dexamethasone impurity 80 (CAS CATO-C4X-116580)
- Regorafenib Impurity 39 (CAS CATO-C4X-104739)
- Daprodustat Impurity 30 (CAS CATO-C4X-240730)
- 1-(Pyridin-3-yl)-1H-pyrazole-4-carboxylic acid (CAS 1014631-89-0)
- (3,5-Dibromothiophen-2-yl)boronic acid (CAS 1095177-31-3)
- 1-(3-Chloro-2-methylphenyl)pyrrolidine (CAS 1020253-09-1)
- 2-((Piperidin-3-ylamino)methyl)benzonitrile hydrochloride (CAS 1353989-83-9)
- (+/-)-2-Methylnicotine (CAS 64114-31-4)
- Heptanophenone (CAS 1671-75-6)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
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