Losartan impurity 32 CAS CATO-C4X-168332
| CAS No. | CATO-C4X-168332 |
| Molecular Formula | C40H34BrClN6 |
| Molecular Weight | 714.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Losartan impurity 32 (C40H34BrClN6) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Losartan impurity 32 (CAS CATO-C4X-168332) is a certified pharmaceutical impurity reference standard with the molecular formula C40H34BrClN6 and a molecular weight of 714.10 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Losartan impurity 32 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C40H34BrClN6 |
| Molecular Weight | 714.10 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 26.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 6 |
Related Losartan Standards
- Losartan Impurity N3 (CAS 133910-00-6)
- Losartan Impurity 52 (CAS CATO-C4X-168352)
- Losartan EP Impurity H (CAS 133909-99-6)
- Losartan EP Impurity I (CAS 1006062-28-7)
- Losartan Impurity N13 (CAS 133727-10-3)
- Losartan Impurity 20 (CAS 1846587-44-7)
- Losartan Impurity 27 (CAS CATO-C4X-168327)
- Losartan EP Impurity L (CAS 230971-71-8)
Recommended Standards
- Palladium, [1,3-bis[2,6-bis(1-methylethyl)phenyl]-1,3-dihydro-2H-imidazol-2-ylidene]dichloro(4,5-dihydro-2-phenyloxazole-ÎșN3)-, (SP-4-1)- (CAS 1586000-47-6)
- Allisartan Isoproxil Impurity 20 (CAS CATO-C4X-321720)
- Pipotiazine Palmitate (CAS 37517-26-3)
- Perfluorotetradecanoic Acid (CAS 376-06-7)
- Zolmitriptan Impurity 31 (CAS CATO-C4X-135131)
- Ferulic Acid Impurity 1 (CAS 2931-90-0)
- Econazole impurity 23 (CAS 1165796-83-7)
- 2-Aminoethyl hydrogen sulfate (CAS 926-39-6)
- 4,4-((1E,1E)-Anthracene-9,10-diylbis(ethene-2,1-diyl))bis(N,N-diphenylaniline) (CAS 155139-11-0)
- 2-(Aminomethyl)benzo[d]thiazol-6-ol (CAS 1176775-02-2)
- Almotriptan USP RC B (Base) (CAS 181178-24-5)
- 2,4-Dichloro-3-methoxy-6-(trifluoromethyl)pyridine (CAS 1214377-90-8)
- 3,3,3-Trifluoro-1-(p-tolyl)propan-1-amine (CAS 1016760-58-9)
- Peptide YY (13-36) (canine, mouse, porcine, rat) (CAS 86895-09-2)
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