Losartan Impurity N13 CAS 133727-10-3
| CAS No. | 133727-10-3 |
| Molecular Formula | C41H37ClN6O |
| Molecular Weight | 665.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C41H37ClN6O, Losartan Impurity N13 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 665.23 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Losartan Impurity N13 (CAS 133727-10-3, C41H37ClN6O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Losartan Impurity N13 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C41H37ClN6O |
| Molecular Weight | 665.23 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 26.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Losartan Standards
- Losartan EP Impurity H (CAS 133909-99-6)
- Losartan EP Impurity I (CAS 1006062-28-7)
- Losartan Impurity N3 (CAS 133910-00-6)
- Losartan impurity 32 (CAS CATO-C4X-168332)
- Losartan Impurity 27 (CAS CATO-C4X-168327)
- Losartan N1-Glucuronide (CAS 138584-34-6)
- Losartan N2-Glucuronide (CAS 138584-35-7)
- Losartan Impurity 52 (CAS CATO-C4X-168352)
Recommended Standards
- N-Trithyl Losartan (CAS 124751-00-4)
- (3-((Triisopropylsilyl)ethynyl)-4-((trimethylsilyl)ethynyl)-hexa-3-en-1,5-diyne-1,6-diyl)bis(triisopropylsilane) (CAS 142761-77-1)
- Gold, [4-(diphenylphosphino-κP)-N,N-dimethylbenzenamine](pentafluoropropanoato-κO)- (CAS 465500-50-9)
- Nicotinic Acid Adenine Dinucleotide (CAS 6450-77-7)
- Creatine impurity 20 (CAS CATO-C4X-120920)
- Elagolix Impurity 83 (CAS CATO-C4X-206883)
- Lansoprazole EP Impurity C/USP Impurity B (CAS 103577-40-8)
- methyl 3-(2-fluorophenyl)-1H-pyrazole-5-carboxylate (CAS 1239717-20-4)
- 2,6-Dichloro-4-fluoroacetophenone (CAS 1804886-00-7)
- 4,6-Bis(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-3-ol (CAS 89990-37-4)
- 5-Chloro-3-iodo-1-methyl-1H-pyrazole (CAS 2585063-96-1)
- 2-(4-Amino-2h-1,2,3-triazol-2-yl)acetic acid (CAS 1368124-71-3)
- N-Cyclohexyl-2-(4-ethylphenyl)quinolin-4-amine (CAS 853331-02-9)
- (D-Ala2)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt (CAS 444073-04-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com