Hydroxychloroquine Impurity 75 CAS 100713-49-3
| CAS No. | 100713-49-3 |
| Molecular Formula | C13H15ClN2O2 |
| Molecular Weight | 266.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Hydroxychloroquine Impurity 75 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Hydroxychloroquine Impurity 75 (CAS 100713-49-3, C13H15ClN2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Hydroxychloroquine Impurity 75 (C13H15ClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H15ClN2O2 |
| Molecular Weight | 266.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Hydroxychloroquine Standards
- Hydroxychloroquine EP Impurity E (CAS 10500-64-8)
- Hydroxychloroquine RC 2 (CAS 860715-45-3)
- Hydroxychloroquine impurity 84 (CAS CATO-C4X-183584)
- Hydroxychloroquine Impurity 70 (CAS 56881-09-5)
- Hydroxychloroquine Impurity 28 (CAS CATO-C4X-183528)
- Hydroxychloroquine Impurity 45 (CAS CATO-C4X-183545)
- Hydroxychloroquine impurity 62 (CAS CATO-C4X-183562)
- Hydroxychloroquine impurity 83 (CAS CATO-C4X-183583)
Recommended Standards
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- Baloxavir Marboxil Impurity 200 (CAS CATO-C4X-2108200)
- CAS 230615-56-2 (CAS 230615-56-2)
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- methyl 2-isothiocyanatopropanoate (CAS 21055-39-0)
- N,N,4-Trimethyl-5-(1-tosylpyrrolidin-2-yl)pyridin-2-amine (CAS 1352537-67-7)
- N-Nitroso Labetalol (Mixture of Diastereomers) (CAS 2820170-74-7)
- (E)-3-Ethyl-2-(4-(1,2,2-triphenylvinyl)styryl)benzo[d]thiazol-3-ium hexafluorophosphate(V) (CAS 1393652-42-0)
- 4-Chloro-3-(2,5-dimethylphenyl)-3-fluoropropiophenone (CAS 898753-69-0)
- Semaglutide impurity 250 (CAS CATO-C4X-2226250)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com