Baclofen impurity 42 CAS 101466-69-7
| CAS No. | 101466-69-7 |
| Molecular Formula | C11H12ClNO4 |
| Molecular Weight | 257.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Baclofen impurity 42 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Baclofen impurity 42 (CAS 101466-69-7, C11H12ClNO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Baclofen impurity 42 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 257.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H12ClNO4 |
| Molecular Weight | 257.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Baclofen Standards
- Baclofen impurity 13 (CAS CATO-C4X-101213)
- Baclofen impurity 26 (CAS CATO-C4X-101226)
- Baclofen Impurity 7 (CAS 5045-65-8)
- Baclofen Impurity 70 (CAS CATO-C4X-101270)
- Baclofen impurity 8 (CAS 19411-80-4)
- Baclofen impurity 29 (CAS CATO-C4X-101229)
- Baclofen EP Impurity F (CAS 4846-95-1)
- Baclofen Impurity 47 (CAS CATO-C4X-101247)
Recommended Standards
- Mosapride Impurity 15 (CAS 112914-09-7)
- 2-amino-3-(4-(2-chloroacetoxy)phenyl)propanoic acid (CAS CATO-C3D-262531)
- etoclopramide Impurity 13 (CAS CATO-C4X-141513)
- 50537-08-1 2-(3-Chloro-4-nitro-phenyl)-propionic acid ethyl ester MFCD11053616 (CAS 50537-08-1)
- Pregabalin Impurity 65 (CAS 869-02-3)
- Selexipag Impurity 37 HCl (CAS CATO-C4X-196137)
- Triclabendazole EP Impurity A (CAS 100648-13-3)
- 5-Bromo-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-6-carboxylic acid (CAS 1227267-00-6)
- Atogepant Impurity 3 (CAS 1455358-11-8)
- (1S,2S,4R)-7-((Benzyloxy)carbonyl)-7-azabicyclo[2.2.1]heptane-2-carboxylic acid (CAS 1932016-35-7)
- 4-Propylpicolinimidamide hydrochloride (CAS 1179362-19-6)
- (E)-Ethyl 3-(pyrrolidin-1-yl)acrylate (CAS 65651-80-1)
- N-(4-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2-methoxyacetamide (CAS 2246895-78-1)
- Thymopoietin II Peptide Fragment (CAS 56795-64-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com