Clarithromycin EP Impurity D CAS 101666-68-6
| CAS No. | 101666-68-6 |
| Molecular Formula | C37H67NO13 |
| Molecular Weight | 733.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Clarithromycin EP Impurity D (CAS 101666-68-6), a pharmacopoeial impurity reference standard (molecular formula C37H67NO13, MW 733.93 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Clarithromycin EP Impurity D is typically off-white to pale yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 733.93 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C37H67NO13 |
| Molecular Weight | 733.93 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 1 |
Related Clarithromycin Standards
- Clarithromycin EP Impurity B (CAS 299409-85-1)
- Clarithromycin EP Impurity N (CAS 144604-03-5)
- Clarithromycin impurity 14 (CAS 138109-92-9)
- Clarithromycin (CAS 81103-11-9)
- Clarithromycin EP Impurity J(Roxithromycin EP Impurity C) (CAS 111321-02-9)
- Clarithromycin EP Impurity M (CAS 127182-43-8)
- Clarithromycin-N-methyl-d3 (CAS 959119-22-3)
- Clarithromycin-D3 (CAS 959119-17-6 (unlabeled))
Recommended Standards
- EH44 (CAS 1879076-81-9)
- Erythromycin EP Impurity M (CAS 616234-56-1)
- Nonan-5-yl (Z)-11-(2-(4-((9-(dimethylamino)-5H-benzo[a]phenoxazin-5-ylidene)amino)phenyl)acetoxy)undecanoate (CAS 136499-31-5)
- Erythromycin EP Impurity J (CAS 105900-46-7)
- Phenylephrine Impurity 102 (CAS 1312706-19-6)
- Baricitinib Impurity 8 (CAS 2402776-84-3)
- Lorazepam Impurity 8 (CAS 2848-96-6)
- 2-Methyl-4-(methylsulfonyl)aniline (CAS 252562-00-8)
- Methyl 2-amino-2-methyl-4-(1h-1,2,4-triazol-1-yl)pentanoate (CAS 1339217-04-7)
- (1-Ethyl-1,2,3,4-tetrahydroquinolin-8-yl)boronic acid (CAS 2856022-81-4)
- [6-ethyl-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 1018125-51-3)
- Bepotastine Impurity 4 (CAS 210095-58-2)
- (R)-Amlodipine-d4 (CAS 1346616-97-4)
- Semaglutide Impurity 152 xTFA (CAS CATO-C4X-2226152)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com