Regorafenib Monohydrate CAS 1019206-88-2
| CAS No. | 1019206-88-2 |
| Molecular Formula | C21H15ClF4N4O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C21H15ClF4N4O3H2O, Regorafenib Monohydrate contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 500.83 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Regorafenib Monohydrate (CAS 1019206-88-2) is a high-purity analytical reference standard with the molecular formula C21H15ClF4N4O3H2O and a molecular weight of 500.83 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Regorafenib Monohydrate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H15ClF4N4O3 H2O |
| Molecular Weight | 500.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Regorafenib Standards
- Regorafenib Impurity 58 (CAS 103842-00-8)
- Regorafenib Impurity 66 (CAS 114780-06-2)
- Regorafenib Impurity 4 (CAS 1187945-05-6)
- Regorafenib Impurity 50 (CAS 1243474-97-6)
- Regorafenib D3 (CAS 1255386-16-3)
- Regorafenib Impurity N2 (CAS 1333390-56-9)
- Regorafenib Impurity 16 (CAS 1343498-71-4)
- Regorafenib Impurity 15 (CAS 1343498-72-5)
Recommended Standards
- Ethyl (E)-(3-(furan-2-yl)acryloyl)glycinate (CAS 103972-52-7)
- 1-Methoxydibenzo[b,d]furan-4-carbonitrile (CAS 1956331-47-7)
- tert-Butyl (2-iodo-6-methoxyphenyl)carbamate (CAS 194869-15-3)
- n-(2-(Cyclohex-1-en-1-yl)ethyl)tetrahydrothiophen-3-amine (CAS 1038286-33-7)
- 3-(((3-(Hydroxymethyl)-1-methyl-1H-pyrazol-5-yl)methyl)thio)naphthalen-1-ol (CAS 2245716-32-7)
- Methyl (2S,4R)-4-fluoro-5-oxopyrrolidine-2-carboxylate (CAS 95048-75-2)
- 2-Chloro-1-isopropyl-4-nitrobenzene (CAS 52756-37-3)
- 2-Mercaptocyclohexanone (CAS 42904-05-2)
- N-(3-Methylbutan-2-yl)thieno[2,3-b]quinoline-2-carboxamide (CAS 478079-48-0)
- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com