2-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid CAS 1019348-55-0
| CAS No. | 1019348-55-0 |
| Molecular Formula | C14H10ClFO3 |
| Molecular Weight | 280.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid (CAS 1019348-55-0), molecular formula C14H10ClFO3 and molecular weight 280.68 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system, 2-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 280.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H10ClFO3 |
| Molecular Weight | 280.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 5-Chloro-2-((3-fluorobenzyl)oxy)benzoic acid (CAS 1002312-89-1)
- 1-(3-chloro-2-fluorophenyl)-1H,4H,5H,6H-cyclopenta[c]pyrazole-3-carboxylic acid (CAS 1038738-53-2)
- 5-chloro-6-[(5-fluoro-2-methylphenyl)amino]pyridine-3-carboxylic acid (CAS 1040006-05-0)
- 4-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid (CAS 1041536-98-4)
- 3-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid (CAS 1041558-34-2)
- 2-(2-Chloro-4-fluorophenoxy)-2-phenylacetic acid (CAS 1082401-01-1)
- 3-Chloro-5'-fluoro-2'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (CAS 1097085-11-4)
- 2-(3-chloro-4-fluorophenoxy)-2-phenylacetic acid (CAS 1097168-10-9)
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