2-(2-Chloro-4-fluorophenoxy)-2-phenylacetic acid CAS 1082401-01-1
| CAS No. | 1082401-01-1 |
| Molecular Formula | C14H10ClFO3 |
| Molecular Weight | 280.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-Chloro-4-fluorophenoxy)-2-phenylacetic acid.
CATO supplies 2-(2-Chloro-4-fluorophenoxy)-2-phenylacetic acid (CAS 1082401-01-1), a certified reference material (molecular formula C14H10ClFO3, MW 280.68 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system, 2-(2-Chloro-4-fluorophenoxy)-2-phenylacetic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 280.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(2-Chloro-4-fluorophenoxy)-2-phenylacetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H10ClFO3 |
| Molecular Weight | 280.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 5-Chloro-2-((3-fluorobenzyl)oxy)benzoic acid (CAS 1002312-89-1)
- 2-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid (CAS 1019348-55-0)
- 1-(3-chloro-2-fluorophenyl)-1H,4H,5H,6H-cyclopenta[c]pyrazole-3-carboxylic acid (CAS 1038738-53-2)
- 5-chloro-6-[(5-fluoro-2-methylphenyl)amino]pyridine-3-carboxylic acid (CAS 1040006-05-0)
- 4-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid (CAS 1041536-98-4)
- 3-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid (CAS 1041558-34-2)
- 3-Chloro-5'-fluoro-2'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (CAS 1097085-11-4)
- 2-(3-chloro-4-fluorophenoxy)-2-phenylacetic acid (CAS 1097168-10-9)
Recommended Standards
- 1-(4-chloro-2-fluorophenyl)-1H,4H,5H,6H-cyclopenta[c]pyrazole-3-carboxylic acid (CAS 1152536-23-6)
- 1-(5-chloro-2-fluorophenyl)-1H,4H,5H,6H-cyclopenta[c]pyrazole-3-carboxylic acid (CAS 1156854-36-2)
- 5'-Chloro-4-fluoro-2'-methoxy-[1,1'-biphenyl]-2-carboxylic acid (CAS 1178334-17-2)
- 2-(2-(4-Fluorophenoxy)-5-chlorophenyl)acetic Acid (CAS 1242014-98-7)
- 2-Hydrazinyl-4-methyl-5-nitropyridine (CAS 15367-24-5)
- 3-(2-Chlorobenzyl)-2-mercapto-4-oxo-3,4-dihydroquinazoline-7-carboxylic acid (CAS 361150-31-4)
- N-(4-Phenylbutyl)piperazin-1-amine (CAS 1159687-56-5)
- 5-(Bromomethyl)-2-(methylthio)pyrimidine (CAS 323591-23-7)
- Lumateperone Impurity 15 (CAS CATO-C4X-220115)
- 7-Bromo-1-methyl-2,3-dihydro-1H-indol-2-one (CAS 100831-25-2)
- 3-(3-Fluoro-4-methylphenyl)propan-1-ol (CAS 1036395-91-1)
- 2-Chloro-N-(2-chloropyridin-3-yl)acetamide (CAS 379726-55-3)
- 7-Chloro-3-(2-chlorophenyl)-5-methyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 1019918-60-5)
- Semaglutide Impurity 140 (CAS CATO-C4X-2226140)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com